The objective was to determine whether mismatch negativity (MMN) is suitable to supplement subjective psychometric subtests of central hearing. We assessed 13 healthy children and 32 children with central auditory processing disorder (CAPD). Three different types of sound deviants were presented in a multi-deviant MMN design. At group level, the incidence of MMN was always higher in clinically diagnosed controls. Children with better results in the subtest Auditory Memory Span had a higher incidence of MMN. The controls also had peak latencies that occurred significantly earlier in frontal, central and temporal electrode sites. The area under the curve (AUC) displayed an asymmetric distribution in CAPD children, who tended to have a left-hemispheric dominance. AUC, peak latency, and the incidence of MMN reflected the discriminative ability of CAPD children. Hence, these characteristics could be used for investigating children with deficits in central hearing and can supplement psychometric tests.

Keywords:
Mismatch negativity, Auditory event-related potential, Preschool children, Central auditory processing disorder
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© 2009 S. Karger AG, Basel
2009
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