In traditional medicine, especially CAM, the concept of (herbal) tonics has a long history in the different medical systems (TEN -- Traditional European Naturopathy; TCM - Traditional Chinese Medicine). Nevertheless, the ideas concerning the function of a tonic differ, e.g., stimulation of body functions, strengthening of organ function, enhancement of adaption, and well-being. Although no exact pharmacodynamic or pharmacokinetic properties of tonics can be given, the following general definition, even in the transcultural comparison between European and Chinese concepts, seems meaningful: A tonic is an agent that has the capability to restore and/or maintain the physiological functioning of an organ system, leading to the subjective feeling of well-being of the patient treated with it.

1.
Starkenstein E: Tonika und Roborantia. Empirisch eingeführte Arzneimittel und ihre experimentell-pharmakologische Analyse. Swiss Med Wkly 1934;49:1124-1229.
2.
Alghabban A (ed): Tonic; in Pharmaceutical Medicine Dictionary. Edinburgh, Churchill Livingstone, 2001.
3.
Stedman TL (ed): Tonic; in Stedman's Medical Dictionary, ed 26. Baltimore, Williams and Wilkins, 1995.
4.
Rätsch C, Müller-Ebeling C: Drachen; in Lexikon der Liebesmittel. Pflanzliche, mineralische, tierische und synthetische Aphrodisiaka. Aarau, AT Verlag, 2003.
5.
Marilyn Farms Company. Super Force - an effective all-purpose tonic that improves circulation and immune response. www.marilynfarms.com/products/super-force.html-0 (access 11.11.14).
6.
Teeguarden R: Chinese Tonic Herbs. New York, Japan Publications, 1984.
7.
Meredith Davies B: Public Health, Preventive Medicine and Social Services, ed 6. London, Edward Arnold, 1995.
8.
Mills S, Bone K: Principles and Practice of Phytotherapy. Modern Herbal Medicine. Edinburgh, Churchill Livingstone, 2000.
9.
Bergner P: The Healing Power of Ginseng and the Tonic Herbs. Rocklin, Prima Pulishing, 1996.
10.
Yarnell E, Abascal K, Rountree R: Adaptogens; in Yarnell E, Abascal K, Rountree R (eds): Clinical Botanical Medicine. New Rochelle, Mary Ann Liebert Inc., 2009.
11.
Mowrey DB: Herbal Tonic Therapies. New Canaan, Keats Publishing, 1993.
12.
Weiss RF: Herbal Medicine. Beaconsfield, Beaconsfield Publishers, 1988.
13.
Saller R, Melzer J, Uehleke B, Rostock M: Phytotherapeutische Bittermittel. Schweiz Z Ganzheitsmed 2009;21:200-205.
14.
Saller R, Reichling J, Rostock M, Iten F, Melzer J: Gastrointestinal symptoms in cancer patients - possible phytotherapy approaches. Schweiz Z Ganzheitsmed 2008;20:221-230.
15.
Walker JM: The bitter remedy. Eur J Herbal Med 2003;6:28-33.
16.
Weiss RF, Fintelmann V: Herbal Medicine, ed 2. New York, Thieme, 2000.
17.
Aschner B: Lehrbuch der Konstitutionstherapie. Stuttgart, Hippokrates, 1934.
18.
Stelter W: Zur Wirkungsweise der Roborantien und Tonica (Dissertation). Hamburg, Universität Hamburg, 1949.
19.
Schaarschmidt S: Therapia generalis oder Abhandlung von denen üblichen Artzneien: nach ihren wahren Eigenschaften und Würckungen, nebst der Anweisung zu deren gehörigen Gebrauch. Berlin, Schütz, 1755.
20.
Svoboda R, Lade A: Ayurveda und Traditionelle Chinesische Medizin. Die beiden ältesten Heilsysteme der Welt im Vergleich. Bern, Otto Wilhelm Barth, 2002.
21.
Ahmad S, Rehman S, Ahmad AM, Siddiqui KM, Shaukat S, Khan MS, Kamal YT, Jahangir T: Khamiras, a natural cardiac tonic: an overview. J Pharm Bioallied Sci 2010;2:93-99.
[PubMed]
22.
Olivier DK, van Wyk BE: Bitterness values for traditional tonic plants of southern Africa. J Ethnopharmacol 2013;147:676-679.
[PubMed]
23.
Ko KM, Mak DH, Chiu PY, Poon MK: Pharmacological basis of ‘Yang-invigoration' in Chinese medicine. Trends Pharmacol Sci 2004;25:3-6.
[PubMed]
24.
Amendt G: No drugs, no future. Drogen im Zeitalter der Globalisierung. Frankfurt, Zweitausendeins, 2004.
25.
Han BC: Müdigkeitsgesellschaft. Berlin, Matthes und Seitz, 2010.
26.
Maier LJ, Liechti ME, Herzig F, Schaub MP: To dope or not to dope: neuroenhancement with prescription drugs and drugs of abuse among Swiss university students. PLoS One 2013;8:e77967.
[PubMed]
27.
Han B-C: Müdigkeitsgesellschaft. Berlin, Matthes und Seitz, 2010.
You do not currently have access to this content.