...: This is a cross-sectional study in which maternal plasma concentrations of pregnancy-associated plasma protease (PAPP)-A, PAPP-A2, insulin-like growth factor-binding protein 1 (IGFBP-1), and IGFBP-4 were determined in the following groups of women: (1) no episodes of preterm labor, term delivery (controls, n...

...Tommasa Quattrocchi; Giovanni Baviera; Teresa Pochiero; Francesca Basile; Laura Rizzo; Angelo Santamaria; Francesco Corrado; Rosario D'Anna Objective: The aim of this study was to investigate whether low first-trimester PAPP-A levels are associated with an adverse pregnancy outcome. Materials...

...Melanie A.J. Engels; Eva Pajkrt; Dominique T. Groot; Roel Schats; Jos W.R. Twisk; John M.G. van Vugt Objective: To validate previously computed correction factors for free β-human chorionic gonadotrophin (fβ-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in in vitro fertilization (IVF...

... Birthright Research Centre for Fetal Medicine, King s College Hospital and bDepartment of Fetal Medicine, University College Hospital, London, and cSchool of Computing and Mathematics, University of Plymouth, Plymouth, UK Key Words First-trimester screening Alpha-Fetoprotein Free -hCG PAPP-A Pyramid...

...Foteini E. Bredaki; David Wright; Pedro Matos; Argyro Syngelaki; Kypros H. Nicolaides Objective: To investigate the potential value of adding maternal serum alpha-fetoprotein (AFP) to free β-human chorionic gonadotropin (β-hCG) and PAPP-A and fetal nuchal translucency (NT) thickness in first...

...David Wright; Argyro Syngelaki; Cahit Birdir; Ivonne Bedei; Kypros H. Nicolaides Objective: To investigate the effect of associations in serum free β-hCG and PAPP-A between successive pregnancies on the performance of screening for trisomy 21 at 11–13 weeks’ gestation. Methods: In 8,499 women...

...H. Abele; K. Lüthgens; M. Hoopmann; K.O. Kagan Objective: To examine the impact of the maternal age-related risk in first-trimester combined screening for trisomy 21. Methods: Prospective assessment of risk for trisomy 21 by a combination of maternal age, fetal NT thickness and maternal serum PAPP...

... between these complications in pregnancies with low pregnancy-associated plasma protein-A (PAPP-A). Methods: Uterine artery PI and serum PAPP-A at 11–13 weeks were measured in 165 cases of PE, including 33 that required delivery before 34 weeks (early PE) and 132 with late PE, and in 301 cases...

... for trisomy 21 Trisomy 18/13 Nuchal translucency PAPP-A Free beta-hCG Prenatal risk calculation PRC ASTRAIA 21 12 2007 11 03 2008 23 10 2008 © 2008 S. Karger AG, Basel 2008 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...