... Myelomeningocele Prophylactic hospitalization Mini-Summary This study confirms that chorioamniotic membrane separation (CMS) is an important complication after open fetal spina bifida (fSB) repair and increases the risk for preterm premature rupture of membranes (PPROM), as well as lower...

... Myelomeningocele Fetal spina bifida repair Middle cerebral artery-Doppler Hindbrain herniation Fetal middle cerebral artery (MCA) Doppler has established its role in prenatal diagnosis and therapy. On the one hand, peak velocity of systolic blood flow in the MCA has been shown a safe marker to replace...

...José Miguel Müller; Edgardo Corral Sereño; Aura Jimenez; Rodrigo Zapata; Silvana Echeverria; Juan Pablo Jara; Alvaro Santibanez; Carolina Lindsay; Renatto Anfossi Introduction: Open spina bifida (OSB) manifests as myelomeningocele (MMC) or myeloschisis (MS). Both lesions theoretically leak...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 MOMS Spina bifida Myelomeningocele MOMS criteria Patient...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Fetal surgery Intrauterine surgery Myelomeningocele Spina bifida Enhanced recovery after surgery Fetal...

... Myelomeningocele Maternal fetal surgery MOMS criteria Mini-Summary What does this study add to current knowledge? The MOMS trial has demonstrated that prenatal repair of spina bifida (SB) significantly improves prognosis. Eligibility criteria for prenatal repair defined for the randomized trial...

... al. [Nat Med. 1995;1(4):342–7], fetal myelomeningocele defect creation and in utero repair demonstrated motor function preservation. The addition of myelotomy in this model can reproduce hindbrain herniation malformations, which is the leading cause of mortality and morbidity in humans. Since...

... 24–48 h postoperative. Inclusion criteria are those of Belfort et al. [ 10 ]: singleton pregnancy, the presence of SBA (including myelomeningocele and myeloschisis), with an upper level (first open vertebra) between T1 and S1, a gestational age under 26 weeks, evidence of Chiari II malformation...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fetal surgery Myelomeningocele...

...Julia Elrod; Nicole Ochsenbein-Kölble; Luca Mazzone; Roland Zimmermann; Christoph Berger; Roberto F. Speck; Nele Strübing; Christoph Mohr; Ueli Moehrlen; Martin Meuli Introduction: In select cases, in utero surgery for myelomeningocele (MMC) leads to better outcomes than postnatal repair. However...

... of dysraphism designated as myelic limited dorsal malformation (MyeLDM) and to describe its characteristics at prenatal ultrasound (US). Methods: It was a retrospective study from 2014 to 2020 based on second-line US evaluation of patients referred to our institution for myelomeningocele (MMC). Magnetic...

... criteria followed the Management of Myelomeningocele Study (MOMS). Team preparation involved observation at the originating center, protocol development, ancillary staff training, and surgical rehearsal using patient-matched models through simulation prior to program implementation. The primary outcome...

... and child outcomes among mothers of young children who were randomized to either prenatal or postnatal surgical closure for myelomeningocele. Methods: Using the Management of Myelomeningocele Study database, maternal depressive risk was examined at 3 time points as follows: prior to birth, 12 months, and 30...

...Sarah C. Stokes; Jordan E. Jackson; Christina M. Theodorou; Christopher D. Pivetti; Priyadarsini Kumar; Kaeli J. Yamashiro; Aijun Wang; Diana L. Farmer Background: The inherent morbidity associated with fetal ovine models of myelomeningocele (MMC) has created challenges for long-term survival...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2021 Fetal surgery Microneurosurgery Minihysterotomy Myelomeningocele Spina bifida...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fetal surgery Spina bifida Myelomeningocele Skin incisions Wound complications Scar assessment The randomized trial of prenatal versus...

...Cara Buskmiller; Chase Pribble; Christopher Quinn Buchanan; Allan Fisher Objective: Function of the lower extremities after prenatal myelomeningocele (MMC) repair is best assessed with ambulatory function at 30–36 months of age, but parents often ask about function before this milestone. Lower...

...Anita Olejek; Ewa Horzelska; Jacek Zamłyński; Tomasz Horzelski; Mateusz Zamłyński; Leszek Nowak; Agnieszka Pastuszka Introduction: The main aim of the fetal surgery of myelomeningocele (MMC) is the improvement in prognosis for children with this defect and at the same time high safety...

...Julie S. Moldenhauer; Shelly Soni; Jillian Jatres; Juliana Gebb; Nahla Khalek; Christina Paidas Teefey; Mark P. Johnson; Alan W. Flake; Holly L. Hedrick; William H. Peranteau; Gregory G. Heuer; N. Scott Adzick Background: Open maternal-fetal surgery for in utero closure of myelomeningocele (MMC...

... intrauterine neurosurgical repair following the protocol from the Management of Myelomeningocele Study (MOMS) trial. Pediatric follow-up with infants reaching 12 and 30 months of life was also reviewed. Results: Fifty-eight fetuses with OSB underwent intrauterine repair at an average (±SD) gestational age...