...Johanna Tiechl; Samira Abdel Azim; Katharina Leitner; Astrid Berger; Irene Mutz-Dehbalaie; Georg Goebel; Matthias Scheier Objective: The aim of this study was to investigate the performance of screening for open spina bifida (OSB) integrated into the routine first-trimester screening. Method...

... characteristics 11–14 weeks scan First-trimester screening Preeclampsia Biochemical markers Uterine artery Blood pressure Preeclampsia is an important cause of maternal and perinatal morbidity and mortality, affecting about 2–10% of the pregnancies [ 1 ]. The condition is responsible...

... until June 2019, in the middle of the study period, and for this reason these pregnancies were excluded. [email protected] 20 04 2020 29 06 2020 9 9 2020 Cell-free DNA Invasive diagnosis First-trimester screening The first-trimester combined screening has been...

... DNA Contingent screening Combined test Fetal trisomy First-trimester screening Prenatal diagnosis The data for this study were derived from prospective screening for trisomy 21 at 11–13 weeks’ gestation by contingent cfDNA testing on the basis of the results from the FCT. All women...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2018 Combined test Cell-free DNA Twin pregnancies First-trimester screening Chromosomal abnormalities The combination of maternal age, fetal nuchal translucency (NT...

...: Of all scans, 38.6% were dating scans and 61.4% were part of first-trimester screening. Anomalies were diagnosed prenatally in 200 (1.8%) fetuses; 81 (0.7%) were chromosomal and 119 (1.1%) were structural. Of all prenatally detected anomalies, 27% ( n = 32) were detected at first-trimester scan...

.... [email protected] 10 07 2017 21 09 2017 26 10 2017 First-trimester screening Cleft lip and palate Nonchromosomal abnormalities Midsagittal view Nuchal translucency Cleft lip and palate (CLP) is a major contributor to fetal defects. It is found in about 62...

... was 80.6% (95% CI 64.0-91.8) for PE at <37 weeks and 31.8% (95% CI 18.6-47.6) for PE at ≥37 weeks, at a 10% FPR. Conclusion: Our data suggest that the FMF algorithm provides effective first-trimester screening for preterm PE. [email protected] 28 03 2017 29 05 2017 18 7 2017...

... KH: First-trimester screening for trisomies 21, 18 and 13 by ultrasound and biochemical testing. Fetal Diag Ther 2014;35:118-126. 12. Fan HC, Blumenfeld YJ, Chitkara U, Hudgins L, Quake SR: Non-invasive diagnosis fetal aneuploidy by shotgun sequencing DNA from maternal blood. PNAS 2008;105:16266...

... in the false-positive rates (2.23 vs. 9.97%, p < 0.001). Discussion: Sonographers should be aware that removing NT from combined first-trimester screening would result in a 5-fold increase in false-positive rate to maintain the expected detection rates. This should be an incentive for maintaining quality...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. First-trimester screening Trisomy 21 Nuchal translucency Congenital heart defect Due to the common policy...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2014 Gestational diabetes mellitus First-trimester screening Pyramid of pregnancy care Gestational diabetes mellitus (GDM) is associated with an increased risk...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Preeclampsia First-trimester screening Human chorionic gonadotropin receptor Placental growth factor Soluble Fms-like tyrosine kinase-1 Preeclampsia (PE...

... of OC. Methods: A total of 5,054 women with singleton pregnancies underwent first-trimester screening for Down syndrome at 11-13 +6 weeks. The RNT was scanned in each fetus, and 3D volumetric images of cases with abnormal or indeterminate RNT were obtained. Results: Satisfactory images were obtained...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Biochemical markers Down syndrome First-trimester screening Nuchal translucency First-trimester screening for Down syndrome (DS), Edwards syndrome and Patau...

... history were prospectively recorded at the time of first-trimester screening and entered in our database. The following variables were registered: maternal age at first-trimester screening, racial origin (White, Black, Latin-American, and others), nulliparity (no previous deliveries after 24 weeks...

... 2013 3 01 2014 8 2 2014 Cell-free DNA testing Chorionic villus sampling Fetal karyotyping Aneuploidies First-trimester screening Diagnosis of fetal chromosomal abnormalities relies on invasive testing, by chorionic villus sampling (CVS) or amniocentesis...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Non-invasive prenatal testing Fetal aneuploidy Sex chromosome aneuploidy First-trimester screening Prenatal...

... to in the content or advertisements. Cell-free DNA testing Prenatal diagnosis Fetal aneuploidy Twin pregnancy First-trimester screening Cell-free DNA (cfDNA) testing in maternal blood has been successfully applied in singleton pregnancies and shown to provide effective screening for trisomy 21...

... were age, racial origin, smoking status during pregnancy, method of conception and weight, which was measured at the time of screening. We had 207 stored plasma samples obtained at 11-13 weeks' gestation from twin pregnancies undergoing first-trimester screening for trisomies by a combination...