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Keywords: Extravillous trophoblast
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Journal Articles

Characterization of Fetal Cells from the Maternal Circulation by Microarray Gene Expression Analysis - Could the Extravillous Trophoblasts Be a Target for Future Cell-Based Non-Invasive Prenatal Diagnosis?

Subject Area:
Genetics , Women's and Children's Health
Lotte Hatt, Marie Brinch, Ripudaman Singh, Kristine Møller, Rune Hoff Lauridsen, Niels Uldbjerg, Berthold Huppertz, Britta Christensen, Steen Kølvraa
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2014) 35 (3): 218–227.
https://doi.org/10.1159/000356073
Published Online: 09 November 2013
... to be expressed in the placenta, especially in extravillous trophoblasts (EVTs). Immunohistochemical staining of placental tissue confirmed CD105 staining in EVTs and 76% of fetal cells enriched by CD105 were found to be cytokeratin-positive. Discussion: The unique combination of mesodermal (CD105) and ectodermal...
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