... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Trisomy 21 Down syndrome NIPS...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Aneuploidy Cisterna magna Down syndrome First-trimester marker Posterior fossa Prenatal diagnosis Recent advances in ultrasound...

... Economic evaluation Cell-free DNA Genetic testing Fetal diagnosis Down syndrome Trisomy Prenatal screening for trisomy 21 (Down syndrome, T21), trisomy 18 (Edwards syndrome, T18), and trisomy 13 (Patau syndrome, T13) is routinely offered to pregnant women in most European countries. The most...

... angiogenic factors in the amniotic fluid of women carrying foetuses with Down syndrome (DS). Methods: After analysis of the karyotyping results, for the purpose of this study, we chose 12 women with foetal DS. For the control group, we selected 12 healthy patients with uncomplicated pregnancies (15-18 weeks...

.... The data of all fetuses with Down syndrome were provided by the French West Indies Register of Congenital Malformations (REMALAN). Results: There was a significant linear association between fetal NBL and GA (R 2 = 0. 354). The 50th percentile for NBL increased from 5.0 to 7.0 mm from week 20 to 24...

... from any ideas, methods, instructions or products referred to in the content or advertisements. 26 02 2016 27 06 2016 23 7 2016 Diagnosis Down syndrome First trimester Pregnancy outcome Prenatal screening Screening Trisomy 21 Chromosomal abnormalities Pregnancy...

...Olga Sánchez; Carmen Domínguez; Aina Ruiz; Irene Ribera; Jaume Alijotas; Lluís Cabero; Elena Carreras; Elisa Llurba Introduction: Forty percent of Down syndrome (DS) fetuses have congenital heart defects (CHD). An abnormal angiogenic environment has been described in euploid fetuses with CHD...

...Emmeline Calkoen; Bauke Adriaanse; Monique Haak; Margot Bartelings; Adam Kolesnik; Cezary Niszczota; John van Vugt; Arno Roest; Nico Blom; Adriana Gittenberger-de Groot; Monique Jongbloed Background: Congenital heart disease is present in 44-56% of fetuses with Down syndrome (DS...

...-trimester Down syndrome (DS) fetuses. Methods: Prenatal databases were searched for cases of continuing DS pregnancies with serial measurements, taken at least two weeks apart. Trends were plotted on previously reported normal ranges. Results: Serial measurements were available in 25 Down syndrome fetuses...

...C.F. Poon; W.C. Tse; K.O. Kou; K.Y. Leung Objectives: To investigate how the introduction of noninvasive prenatal testing (NIPT) influenced women's testing choices following a positive Down syndrome screening. Methods: A retrospective study was conducted to compare differences in the uptake rates...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Aneuploidy Down syndrome Fetal...

...Melanie A.J. Engels; Jos W.R. Twisk; Marinus A. Blankenstein; John M.G. van Vugt Introduction: The objective of this study was to evaluate the performance of first-trimester Down syndrome (DS) screening with serum sampling at different weeks of gestation. Material and Methods: We studied 35,431...

... attended for first-trimester combined screening assessment of risk of Down syndrome were invited to participate in an interviewer-administered survey. Women were asked to choose between NIDT (variable detection rate but no miscarriage risk) and IPD (∼100% detection rate but 0.5-1% miscarriage risk...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Assisted reproduction Down syndrome First-trimester screening Free β-hCG PAPP-A Prenatal screening for chromosomal abnormalities has become part of routine antenatal care in the Netherlands...

... their efficacy in expanded and contingent screening strategies for Down syndrome. Material and Methods: NB, DV and TF were assessed in 11,261 singleton fetuses undergoing first trimester combined screening. For each marker, Down syndrome detection rate (DR), false positive rate (FPR), positive, negative...

.... Ductus venosus Prenatal screening Trisomy 21 Down syndrome Ultrasound markers Ductus venosus (DV) blood velocities assessment has demonstrated to improve the effectiveness of first-trimester combined screening for trisomy 21 [ 1 ], used either as a qualitative marker (present vs. absent...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Screening Trisomy 21 Down syndrome Maternal blood Noninvasive prenatal diagnosis Review Fetal Diagn Ther 2012;31:81 86 DOI: 10.1159/000333060 Received: July 19, 2011...

...C. Ramalho; O. Brandão; A. Matias; N. Montenegro Objectives: Evaluation of morphological and morphometric characteristics of fetuses with Down syndrome based on a detailed postmortem examination and comparison of these fetuses with a control group of fetuses with normal karyotype to improve...

..., instructions or products referred to in the content or advertisements. Cordocentesis Doppler velocimetry Down syndrome Hydrops fetalis Intrauterine death Hepatosplenomegaly Novel Insights from Clinical Practice Fetal Diagn Ther 2011;29:325 330 DOI: 10.1159/000323582 Received: July 22, 2010...

.... In fetuses prior to 24 weeks with NIHF, a chromosomal anomaly is a common association. TAM is a leukaemic condition, almost entirely limited to children with Down syndrome. The presentation of TAM prenatally is unusual but cases may present ultrasonographically with NIHF and associated fetal...