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Keywords: Congenital high airway obstruction syndrome
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Journal Articles

In utero Treatment of Congenital High Airway Obstruction Syndrome via Fetal Laryngoscopy and EXIT Procedure

Subject Area:
Genetics , Women's and Children's Health
Rana Sabra, Ciprian P. Gheorghe, Martha A. Monson, Jinnen Masri, Ramen H. Chmait
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2022) 49 (9-10): 385–393.
https://doi.org/10.1159/000526798
Published Online: 08 December 2022
...Rana Sabra; Ciprian P. Gheorghe; Martha A. Monson; Jinnen Masri; Ramen H. Chmait Introduction: Congenital high airway obstruction syndrome (CHAOS) is a rare condition that can progress to fetal hydrops and demise in utero or at birth unless interventions are undertaken to alleviate the tracheal...
View article titled, In utero Treatment of <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> via Fetal Laryngoscopy and EXIT Procedure
Open the PDF for In utero Treatment of <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> via Fetal Laryngoscopy and EXIT Procedure in another window
Journal Articles

Fetoscopic Balloon Dilation and Stent Placement of Congenital High Airway Obstruction Syndrome Leading to Successful Cesarean Delivery

Subject Area:
Genetics , Women's and Children's Health
Alice King, Joshua R. Bedwell, Deepak K. Mehta, Gary E. Stapleton, Henri Justino, Caitlin Sutton, Roopali Donepudi, Magdalena Sanz-Cortes, Ahmed A. Nassr, Raphael C. Sun, Timothy C. Lee, Sundeep G. Keswani, Christopher I. Cassady, Amy Mehollin-Ray, Michael A. Belfort
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2022) 49 (1-2): 29–35.
https://doi.org/10.1159/000521664
Published Online: 07 January 2022
... or perinatal intervention, congenital high airway obstruction syndrome (CHAOS) is a fatal anomaly. The ex utero intrapartum treatment (EXIT) procedure has been used to secure the fetal airway and minimize neonatal hypoxia but is associated with increased maternal morbidity. Case Presentation: A 16-year-old...
View article titled, Fetoscopic Balloon Dilation and Stent Placement of <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> Leading to Successful Cesarean Delivery
Open the PDF for Fetoscopic Balloon Dilation and Stent Placement of <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> Leading to Successful Cesarean Delivery in another window
Journal Articles

Fetoscopy-Assisted Percutaneous Decompression of the Distal Trachea and Lungs Reverses Hydrops Fetalis and Fetal Distress in a Fetus with Laryngeal Atresia

Subject Area:
Genetics , Women's and Children's Health
Clara T. Nicolas, David Lynch-Salamon, Ellen Bendel-Stenzel, Robert Tibesar, Francois Luks, Stephanie Eyerly-Webb, Joseph B. Lillegard
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2019) 46 (1): 75–80.
https://doi.org/10.1159/000500455
Published Online: 25 June 2019
...Clara T. Nicolas; David Lynch-Salamon; Ellen Bendel-Stenzel; Robert Tibesar; Francois Luks; Stephanie Eyerly-Webb; Joseph B. Lillegard We present a case of prenatal hydrops secondary to congenital high airway obstruction syndrome (CHAOS) that was treated with fetoscopy-assisted needle decompression...
View article titled, Fetoscopy-Assisted Percutaneous Decompression of the Distal Trachea and Lungs Reverses Hydrops Fetalis and Fetal Distress in a Fetus with Laryngeal Atresia
Open the PDF for Fetoscopy-Assisted Percutaneous Decompression of the Distal Trachea and Lungs Reverses Hydrops Fetalis and Fetal Distress in a Fetus with Laryngeal Atresia in another window
Journal Articles

Experimental Evaluation of Tracheo-Amniotic Shunting for Induced Congenital High Airway Obstruction in a Sheep Model

Subject Area:
Genetics , Women's and Children's Health
Philip DeKoninck, Masayuki Endo, Jan A. Deprest, Luc De Catte
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2015) 38 (4): 282–287.
https://doi.org/10.1159/000381145
Published Online: 16 April 2015
...Philip DeKoninck; Masayuki Endo; Jan A. Deprest; Luc De Catte Objective: To evaluate the feasibility of tracheo-amniotic shunting in a sheep model for congenital high airway obstruction syndrome. Material and Methods: High airway obstruction was induced around day 95 (term = 145 days) in 10 lamb...
View article titled, Experimental Evaluation of Tracheo-Amniotic Shunting for Induced Congenital High Airway Obstruction in a Sheep Model
Open the PDF for Experimental Evaluation of Tracheo-Amniotic Shunting for Induced Congenital High Airway Obstruction in a Sheep Model in another window
Journal Articles

Treatment of a Fetal Tracheal Obstruction by Fetoscopy and Laser

Subject Area:
Genetics , Women's and Children's Health
Sandra Bel, Nicolas Sananes, Adrien Gaudineau, Cherif Akladios, Romain Favre
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2016) 40 (1): 63–66.
https://doi.org/10.1159/000371705
Published Online: 31 January 2015
... A, Keiner S, Muller A, Franz A, Bartmann P, Gembruch U: Fetoscopic and ultrasound-guided decompression of the fetal trachea in a human fetus with Fraser syndrome and congenital high airway obstruction syndrome (CHAOS) from laryngeal atresia. Ultrasound Obstet Gynecol 2006;27:84-88. 3. Wagner W, Harrison...
View article titled, Treatment of a Fetal Tracheal Obstruction by Fetoscopy and Laser
Open the PDF for Treatment of a Fetal Tracheal Obstruction by Fetoscopy and Laser in another window
Journal Articles

Evaluation of Fetal Vocal Cords to Select Candidates for Successful Fetoscopic Treatment of Congenital High Airway Obstruction Syndrome: Preliminary Case Series

Subject Area:
Genetics , Women's and Children's Health
J.M. Martínez, M. Castañón, O. Gómez, J. Prat, E. Eixarch, M. Bennasar, B. Puerto, E. Gratacós
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2013) 34 (2): 77–84.
https://doi.org/10.1159/000350697
Published Online: 27 August 2013
...J.M. Martínez; M. Castañón; O. Gómez; J. Prat; E. Eixarch; M. Bennasar; B. Puerto; E. Gratacós Objective: Congenital high airway obstruction syndrome (CHAOS) normally has a dire prognosis due to laryngeal atresia and association with other anomalies. However, rare cases with an isolated tracheal...
View article titled, Evaluation of Fetal Vocal Cords to Select Candidates for Successful Fetoscopic Treatment of <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span>: Preliminary Case Series
Open the PDF for Evaluation of Fetal Vocal Cords to Select Candidates for Successful Fetoscopic Treatment of <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span>: Preliminary Case Series in another window
Journal Articles

Congenital High Airway Obstruction Syndrome due to Complete Tracheal Agenesis: An Accident of Nature with Clues for Tracheal Development and Lessons in Management

Subject Area:
Genetics , Women's and Children's Health
Sachin S. Vaikunth, Lee M. Morris, William Polzin, William Gottliebson, Foong-Yen Lim, Beth Kline-Faith, Timothy M. Crombleholme
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2009) 26 (2): 93–97.
https://doi.org/10.1159/000242454
Published Online: 10 October 2009
...Sachin S. Vaikunth; Lee M. Morris; William Polzin; William Gottliebson; Foong-Yen Lim; Beth Kline-Faith; Timothy M. Crombleholme Congenital high airway obstruction syndrome (CHAOS) is a life-threatening condition characterized by complete blockage of the fetal airways associated with hydrops. We...
View article titled, <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> due to Complete Tracheal Agenesis: An Accident of Nature with Clues for Tracheal Development and Lessons in Management
Open the PDF for <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> due to Complete Tracheal Agenesis: An Accident of Nature with Clues for Tracheal Development and Lessons in Management in another window
Journal Articles

Successful Fetal Intervention for Congenital High Airway Obstruction Syndrome

Subject Area:
Genetics , Women's and Children's Health
Bettina W. Paek, Peter W. Callen, Joseph Kitterman, Vickie A. Feldstein, Jody Farrell, Michael R. Harrison, Craig T. Albanese
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2002) 17 (5): 272–276.
https://doi.org/10.1159/000063179
Published Online: 12 August 2002
...Bettina W. Paek; Peter W. Callen; Joseph Kitterman; Vickie A. Feldstein; Jody Farrell; Michael R. Harrison; Craig T. Albanese Introduction: Complete congenital high airway obstruction syndrome (CHAOS) usually leads to stillbirth or death within minutes of delivery. We describe the management...
View article titled, Successful Fetal Intervention for <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span>
Open the PDF for Successful Fetal Intervention for <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> in another window
Journal Articles

Salvage of a Fetus with Congenital High Airway Obstruction Syndrome by ex utero Intrapartum Treatment (EXIT) Procedure

Subject Area:
Genetics , Women's and Children's Health
Timothy M. Crombleholme, Karl Sylvester, Alan W. Flake, N. Scott Adzick
Journal: Fetal Diagnosis and Therapy
Fetal Diagn Ther (2000) 15 (5): 280–282.
https://doi.org/10.1159/000021022
Published Online: 04 September 2000
...Timothy M. Crombleholme; Karl Sylvester; Alan W. Flake; N. Scott Adzick A fetus with congenital high airway obstruction syndrome (CHAOS) due to complete tracheal atresia was referred at 31 weeks of gestation after 12 weeks of massive hydrops. The fetus was delivered by the ex utero intrapartum...
View article titled, Salvage of a Fetus with <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> by ex utero Intrapartum Treatment (EXIT) Procedure
Open the PDF for Salvage of a Fetus with <span class="search-highlight">Congenital</span> <span class="search-highlight">High</span> <span class="search-highlight">Airway</span> <span class="search-highlight">Obstruction</span> <span class="search-highlight">Syndrome</span> by ex utero Intrapartum Treatment (EXIT) Procedure in another window