...Megan G. Lord; Matthew A. Esposito; Alexis C. Gimovsky; Stephen R. Carr; Melissa L. Russo Introduction: Chorionic villus sampling (CVS) remains essential for first-trimester genetic diagnosis, yet clinical volume may be insufficient to train new clinicians in the technique. Available simulation...

... of a curriculum for learning chorionic villus sampling (CVS) and amniocentesis (AC) and the items of an assessment tool to evaluate CVS and AC competence. Methods: We used a 3-round iterative Delphi process. A steering committee supervised all processes. Seven international collaborators were identified to expand...

... in pregnancies undergoing amniocentesis (AC) following inconclusive results for a chorionic villus sampling (CVS). Methods: This was a multicentric retrospective cohort study of patients in which both CVS at 11–13 weeks’ gestation and AC at 16–22 weeks were performed between January 1st, 2008, and July 31st...

...Yi Man Wah; Tak Yeung Leung; Yvonne Kwun Yue Cheng; Daljit Singh Sahota Objective: The aim was to determine the institutional procedure-related fetal loss rate after chorionic villus sampling (CVS) and the factors which may identify pregnancies at increased risk of having a procedure-related loss...

...Marcos Cordoba; Stephanie Andriole; Shara M. Evans; David Britt; Melissa Chu Lam; Mark I. Evans Objectives: The explosion in genetic technologies, including array comparative genomic hybridization (aCGH), has increased the complexity of genetic counseling. We now offer chorionic villus sampling...

... study including 5,306 high-risk pregnancies with NT measurements and chorionic villus samples (CVS) tested for full karyotype. Results: The fetal karyotype was normal in 4,172 (78.6%) cases and abnormal in 1,134 (21.4%), including 1,009 with a likely clinically significant adverse outcome. Universal CVS...

...%) in period 2, and 254 (1.2%) in period 3 (p < 0.01). In addition, in 765 (2.5%) cases, chorionic villus sampling (CVS) was performed in period 1, compared to 1,174 (3.0%) cases in period 2 and 251 (1.3%) cases in period 3 (p < 0.01). Advanced maternal age as the sole indication for invasive procedures...

...%, respectively (p < 0.001). Both chorionic villus sampling and amniocentesis decreased in year 1, but only the former in year 2. However, the rate of declining further testing was similar before and after NIPT (p = 0.213). In multivariable analysis, first trimester screening, nulliparity and working women...

... chorionic villus sampling in approximately 85% of cases, obtain fluorescent in situ hybridization (FISH) results overnight, and then perform FR the next day. Decisions about which to reduce prioritize anomalies, but now can include fetal gender in the decision process, as couples are now just as likely...

... and 13. Methods: The prevalence of trisomies 21, 18 or 13, sex chromosome aneuploidies, triploidy and other chromosomal abnormalities was examined in pregnancies undergoing first-trimester combined screening and chorionic villus sampling (CVS). Results: In 1,831 clinically significant chromosomal...

... diagnosis Amniocentesis Chorionic villus sampling Standard gamble Women undergoing Down syndrome screening are generally labeled as either ‘low' or ‘high' risk of having fetal aneuploidy based on their post-test-adjusted risk [ 1 ]. Those indicated as ‘high' risk are offered an invasive prenatal...

...Vatsla Dadhwal; Aparna K. Sharma; Aprajita Singh; Deepika Deka; Suneeta Mittal; Guresh Kumar Objective: To study patient perception of pain and anxiety before and after amniocentesis (AC) and transabdominal chorionic villus sampling (CVS) and the clinical correlates of pain and anxiety. Methods: 92...

... with long-term culture. Novel Insights We report a false-negative finding on chorionic villi due to the presence of an exceptional form of mosaicism confined to the fetus. Key Words Corpus callosum Fetoplacental discrepancy Chorionic villus sampling 18q-Syndrome Abstract We report a case...

...Asma Khalil; Ranjit Akolekar; Argyro Syngelaki; Jose-Maria Perez Penco; Kypros H. Nicolaides Introduction: The aim of this study was to examine the potential effect of chorionic villus sampling (CVS) on placental perfusion by examining the change in uterine artery pulsatility index (PI) between...

.... Amniocentesis Chorionic villus sampling Chromosomal abnormalities Genetic counseling Prenatal counseling Prenatal diagnosis Prenatal screening Original Paper Fetal Diagn Ther 2010;27:149 155 DOI: 10.1159/000295210 Received: September 28, 2009 Accepted after revision: February 2, 2010 Published online...

... of the literature. Results: Data from randomised controlled trials as well as from systematic reviews and a large national registry study are consistent with a procedure-related miscarriage rate of 0.5–1.0% for amniocentesis as well as for chorionic villus sampling (CVS). In single-center studies performance may...

... correlation with the gestational week. Given the high normal background rate of spontaneous abortions in the early period of pregnancy without an invasive procedure, early amniocentesis can be considered as a safe alternative to chorionic villus sampling and standard amniocentesis. Amniocentesis, early...

...R.D. Wilson; W. Gibson; M. Bebbington; M. Walker; D. Shaw The objective of this prospective study was to evaluate the fetal heart rate before and after the procedure and whether this had any effect on the risk of pregnancy loss following chorionic villus sampling (CVS) and chromosomally normal...

...Nelson B. Isada; Mark P. Johnson; Peter G. Pryde; Mordechai Hallak; Mark I. Evans Following the 1990 FDA approval of the Trophocan® catheter for use in transcervical chorionic villus sampling (CVS), an increasing number of US physicians have begun offering the procedure. To obtain privileges...

...Lee P. Shulman; Joe Leigh Simpson; Sherman Elias; Richard E. Felker; Donald S. Emerson; Owen.P Phillips Transvaginal chorionic villus sampling (CVS) using concurrent transabdominal ultrasound guidance was performed in 20 women who desired CVS but could not be offered transcervical or transabdominal...