...F.E. Bredaki; L.C. Poon; C. Birdir; D. Escalante; K.H. Nicolaides Objective: To assess the potential value of maternal serum alpha-fetoprotein (AFP) at 11–13 weeks’ gestation in early screening for fetal neural tube defects (NTDs). Methods: Maternal serum AFP at 11–13 weeks’ gestation was measured...

...Foteini E. Bredaki; David Wright; Ranjit Akolekar; Grasielle Cruz; Kypros H. Nicolaides Objective: To establish a reference distribution of maternal serum alpha-fetoprotein (AFP) at 11–13 weeks’ gestation and define the contribution of maternal variables that influence the measured concentration...

...Foteini E. Bredaki; David Wright; Pedro Matos; Argyro Syngelaki; Kypros H. Nicolaides Objective: To investigate the potential value of adding maternal serum alpha-fetoprotein (AFP) to free β-human chorionic gonadotropin (β-hCG) and PAPP-A and fetal nuchal translucency (NT) thickness in first...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alpha-fetoprotein Hispanic ethnicity Maternal serum screening Neural tube...

...Ariel Jaffa; Yuval Yaron; Joseph Har-Toov; Reuben Amster; Cyril Legum; Joseph B. Lessing Objective: Women with elevated maternal serum alpha-fetoprotein (MSAFP) and normal amniotic fluid alpha-fetoprotein (AFAFP) are at an increased risk of an adverse pregnancy outcome. Such MSAFP elevations...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Aneuploidy Alpha-fetoprotein Multiple-marker...

..., Haifa, Israel; b Coming/MetPath Laboratories, Teterboro, N.J.; c Coming/MetPath Laboratories, Auburn Hills, Mich., and d Division of Reproduction Genetics, Department of Obstetrics and Gynecology, Hutzel Hospital, Wayne State University, Detroit, Mich., USA Key Words Alpha-fetoprotein Human chorionic...

...Arie Drugan; Yuval Yaron; June Murphy; Saleh A.D Ebrahim; Ralph L. Kramer; Mark P. Johnson; Mark I. Evans Objective: To evaluate the effect of fetal sex on the concentration of amniotic fluid alpha-fetoprotein (AF-AFP) in singletons and twins. Material and Methods: Amniocentesis was performed...

...Maria Szabó; Lajos Veress; Ákos Münnich; Zoltán Papp Maternal serum alpha-fetoprotein (MSAFP) concentration values were measured in relation to maternal age and fetal sex in the 16th to 20th gestational weeks in samples taken from 9,556 pregnancies with the outcome of live, mature and healthy...

...Reuven Sharony; Arie Drugan; Aliza Amiel; Julia Grinshpun-Cohen; Shlomo Markov; Moshe D. Fejgin Objectives: To examine the assumption that amniotic fluid alpha-fetoprotein (AFAFP) levels are different in female and male twin fetuses. Design: Amniotic fluid levels of AFP in pregnancies with female...

... Memorial Hospital, Taipei, Taiwan Key Words Down syndrome W Alpha-fetoprotein W Human chorionic gonadotropin W Serum screening W Second trimester Abstract The purpose of the present study is to evaluate the efficacy of second-trimester maternal serum screening program by using ·-fetoprotein (AFP) and total...

... neural tube defects using alpha-fetoprotein and free β-human chorionic gonadotropin as serum markers. Methods: 3,188 women underwent testing between 14th and 22nd week of pregnancy. Of all tested patients, 25.4% were ≥35 years old. A cut-off risk of ≥1:250 for Down’s syndrome and MS-AFP ≥2.0 MoM for open...