...J. Aro; R. Haapiainen; M. Kajanti; S. Rannikko; O. Alfthan; and the Finnprostate Group 151 patients with locally advanced prostatic cancer (T3-4M0), representing 38% of the 404 cancer patients in a Finnish multicenter study, were randomly assigned to one of three treatment arms: orchiectomy...

...Domenico Pescatore; Claudio Giberti; Giuseppe Martorana; Giandomenico Natta; Luciano Giuliani We have studied 38 patients with previously untreated, widespread prostatic cancer, who were submitted to therapy with cyproterone acetate and orchiectomy. 70% of patients with symptoms have shown...

...Luciano Giuliani; Domenico Pescatore; Claudio Giberti; Giuseppe Martorana; Giandomenico Natta We report the results from 106 patients with extracapsular (stage C) or widespread (stage D)prostatic cancer, who were treated with cyproterone acetate and orchiectomy and followed for 5 years. As controls...

...J. Aro; R. Haapiainen; V. Rasi; S. Rannikko; O. Alfthan The effects of parenterally given polyestradiol phosphate (80 or 160 mg i.m. monthly) and bilateral subcapsular orchiectomy on blood coagulation and fibrinolytic parameters were compared in 11 patients with prostatic carcinoma. Estrogen...

.... Prostate cancer Metastases Orchiectomy Luteinizing hormone-releasing hormone Flutamide Cyproterone acetate Nilutamide Leuprolide F.M.J. Debruyne W.P.J. Witjes Department of Urology, University Hospital Nijmegen, The Netherlands EurUrol 1993;24(suppl 2):67 71 1605684 Overview of Current Status...

...F. Calais da Silva Subjective quality-of-life assessments obtained from investigators and patients were compared in a subset of 76 patients from an EORTC study (protocol 30853) on metastatic prostatic carcinoma. In this study the therapeutic effect of orchiectomy was compared with a luteinizing...

...Niels-Peter Buchholz; Gianfranco Mattarelli; Marie-Madeleine Huber Buchholz Orchiectomy is a frequently performed androgen ablative therapy in men with prostatic cancer. Sudden withdrawal of sex steroids in men can lead to troublesome menopausal symptoms such as hot flushes (HF) and profuse...

...R. Tomic; B. Bergman; S.-O. Hietala; T. Angström In 48 patients with prostatic carcinoma two types of cell patterns were found at fine-needle aspiration biopsy at follow-up 6 and 12 months after orchiectomy. (1) unmodified carcinoma cells or (2) carcinoma cells with regressive changes. Objective...

..., it was observed that, due to torsion, the mean seminiferous tubular diameter and percentage of spermatogenetic activity of the contralateral testes were reduced and an inflammatory reaction was also noted. In group 2,detorsion increased the above-mentioned damage, and in group 3, orchiectomy failed to prevent...

...; Estradurin®, 80 or 160 mg/month) with the respective changes in orchiectomized patients. In the estrogen group there was no change in the total serum cholesterol level, whereas in the orchiectomy group an increase of 10% was observed. Estrogen therapy resulted in a significant increase of serum HDL (11...

.... However, in a retrospective matched-pair comparison of radical prostatectomy with pelvic lymphadenectomy plus early orchiectomy and orchiectomy alone, Ghavamian and coworkers [ 5 ]showed that the removal of the prostate increased the chance of survival at 10 years; the combined approach improved both...

... treatment with LH-RH agonist plus antiandrogen was compared with orchiectomy alone, only the European Organization for Research and Treatment of Cancer (EORTC) study 30853 showed a significant difference in favour of CAB. However, in this study an increased proportion of patients receiving CAB may have had...

...Kazunori Kihara; Hiroyuki Oshima Objective: To preserve the appearance of a normal scrotum at orchiectomy, a pedicled fibro-fatty tissue graft was inserted in the lumen of the tunica vaginalis. Methods: 42 testes of 21 patients with metastatic prostate cancer were treated. A pedicled fibro-fatty...