... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemohormonal therapy Immunohormonal therapy Prostate cancer Carcinoma, prostatic Interferons Chemotherapy Flutamide Androgen blockade, total 11 8 2017 Eur Urol...

... testicular and adrenal androgens, seems to be the favored approach. Surgical castration, although effective, seems inferior to depot luteinizing hormone-releasing hormone therapy with respect to patients’ acceptance and preference. Nonsteroidal antiandrogens, such as flutamide,have advantages over steroidal...

... mg/day s.c. in combination with either placebo (n = 300) or flutamide 250 mg p.o.t.i.d. (n =303). The median progression-free survival times were estimated at 14 months for the leuprolide plus placebo group and 17 months for leuprolide plus flutamide patients: median times for overall survival were...

... hormone-releasing hormone analogue depot preparation and flutamide in 327 patients in total. Pretreatment,6- and 12-month quality-of-life assessments revealed large variations between the patients’ and the investigators’ evaluation of performance status and sexual status (potency). Correlation analysis...

...L. Boccon-Gibod The use of nonsteroidal antiandrogens as first-line therapy for the treatment of cancer of the prostate is discussed. The results of studies using flutamide as monotherapy are reviewed and show flutamide to be an effective agent in the treatment of metastatic prostate cancer...

..., advanced Hormonal therapy Androgen blockade, combined Bicalutamide Casodex™ Flutamide Eulexin™ Nilutamide Anandron™ Review Paper EurUrol 1995;28:177-188 F.M.J. Debruynea G.A. Dijkmanb 3 University Hospital, Nijmegen, and b Ignatius Hospital, Breda, The Netherlands Advances and Trends in Hormonal...

... of the 5α-reductase inhibitor finasteride and the antiandrogen flutamide was as effective as a luteinizing hormone-releasing hormone analog and flutamide in inhibiting the growth of the prostate. In a pilot trial, 10 potent patients with clinical stage C and D1 prostate cancer were given the combination...

... dehydrogenase and 5α-reductase. Blockade of DHT synthesized by these enzymes, with a pure antiandrogen of the class of flutamide,prolongs life in advanced prostate cancer, the effect being much more important when a small number of metastases is present. Most importantly, 3-month combination therapy reduces...

...M. Bonard; S. de Almeida; W. von Niederhäusern A double placebo-controlled study using the anti-androgen non-steroidal compound Flutamide in 32 patients with benign enlargement of the prostate is reported. A statistical analysis of the results showed no difference between the group treated...

...F. Di Silverio; F. Sciarra; G. D’Eramo The aim of the present investigation was to establish whether in advanced prostatic carcinoma in relapse treated with LHRH analogues combined with cyproterone acetate (CPA), substitution of this antiandrogen with another compound such as flutamide (FLU) might...

...E.D. Crawford The effectiveness of leuprolide (an LHRH analog), alone or in combination with flutamide (a nonsteroidal antiandrogen) was tested in a double-blind multicenter study involving 603 patients with advanced prostatic cancer. The estimated median survival time was significantly longer...

...W. Oosterlinck; J. Casselman; J. Mattelaer; R. Van Velthoven; O. Kurjatkin; C. Schulman Objective: In a multicenter study, 905 patients with newly diagnosed advanced prostate cancer treated with flutamide were followed for safety and side effects. Methods: Flutamide was administered in monotherapy...

... Bicalutamide Casodex™ Combined androgen blockade Eulexin™ Flutamide Hormonal therapy Nilutamide Patient subgroups Prostate cancer, advanced European Urology F.M.J. Debruyne Department of Urology, University Hospital Nijmegen, The Netherlands EurUrol 1996;29(suppl 2):34-36 1605826 Combined Androgen...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Anandron™ Antiandrogens Bicalutamide Casodex™ Combined androgen blockade Eulexin™ Flutamide Goserelin Nilutamide...

... therapy with Casodex™(bicalutamide, 50 mg once daily) or flutamide (250 mg three times daily) and to luteinising hormone-releasing hormone (LHRH) analogue therapy with Zoladex™ (goserelin, 3.6 mg every 28 days) or leuprolide (7.5 mg every 28 days). Time to treatment failure was the primary efficacy...

...Sophie D. Fosså; Elisabeth Paus During the years 1988-1991 sequential serum prostate-specific antigen (PSA)determinations were performed during systemic treatment of hormone-resistant prostate cancer. The following drugs were used: prednisone (5 mg 4 times per os daily, 8 patients); flutamide (250...

...: We report the results of 402 patients (220 with a clinical T2 tumor and 182 with a clinical T3 tumor) of whom 192 randomly received neoadjuvant total androgen deprivation using a LHRH analogue (goserelin) plus flutamide for a period of 3 months and 210 underwent radical prostatectomy only. Results...

...Keita Fujikawa; Yoshiyuki Matsui; Shigeki Fukuzawa; Hideo Takeuchi Background: Some authors have recently reported that maximum androgen block (MAB), in which the nonsteroidal anti–androgen, flutamide, is used together with conventional hormone therapy such as castration or luteinizing hormone...

...C.J. Tyrrell; J.E. Altwein; F. Klippel; C. Jurincic-Winkler; E. Varenhorst; G. Lunglmayr; F. Boccardo; I.M. Holdaway; J.-M. Haefliger; J.P. Jordaan Objective: The aim of this study was to compare the effects of the nonsteroidal antiandrogen flutamide plus the LH–RH analogue goserelin acetate...

..., either flutamide (n = 56) or cyproterone acetate (n = 65), and had normal pretreatment serum alanine aminotransferase (ALT) levels. Serological markers of hepatitis B and C viruses (HBV and HCV) were checked in 42 of the 121 patients. Results: Twenty-two (18%) of the 121 patients had ALT elevations...