Objectives: To know the incidence of tumoural pathology among our cases of horseshoe kidney (HK), a congenital anomaly occurring in 0.25% of the population, as well as their prognostic factors and follow-up. Methods: A total of 82 patients admitted at our Centre between 1967 and 1996 with an HK diagnosis were retrospectively reviewed. We have collected a total of 10 cases of HK tumours. We analyse the clinical, diagnostic, surgical and evolutionary peculiarities of the different HK tumour aetiologies, as compared with those described in literature. Results: Our experience is based on 10 patients – 5 adenocarcinomas, 4 transitional cell carcinomas and a Wilms’ tumour. Conclusions: We have observed that in the case of transitional cell carcinomas, the diagnosis is generally made at an advanced stage. The prognosis of the tumorous disease depends upon the same prognostic factors as in the case of normal kidneys. Renal adenocarcinoma is the kind of tumour most frequently associated with HKs. Its incidence among the HK cases is not greater than among the normal population. Conservative local treatment criteria for adenocarcinoma should be valid for HKs as well.

Keywords:
Horseshoe kidney, Cancer
1.
Bauer SB, Perlmutter AD, Retik A: Anomalies of the upper urinary tract; in Walsh PC, Retik AB, Stamey TA, Vaughan E (eds): Campbell’s Urology, ed. 6. Philadelphia, Saunders, 1992, pp 1357–1442.
2.
Mesrobian HJ, Kelalis PP, Hrabovsky E, Othersen HB, de Lorimier A, Nenmith B: Wilms tumor in horseshoe kidneys: A report from the National Wilms Tumor Study. J Urol 1985;133:1002–1003.
3.
Murphy DM, Zincke H: Transitional cell carcinoma in the horseshoe kidney: Report of 3 cases and review of the literature. Br J Urol 1982;54:484–485.
4.
Buntley D: Malignancy associated with horseshoe kidney. Urology 1976;8:146–148.
5.
Hohenfellner M, Schultz-Lampel D, Lampel A, Steinbach F, Cramer BM, Thüroff JW: Tumor in the horseshoe kidney: Clinical implications and review of embryogenesis. J Urol 1992;147:1098–1102.
6.
Blackard CE, Mellinger GT: Cancer in horseshoe kidney. A report of two cases. Arch Surg 1968;97:616–627.
7.
Gonzalez Argente FJ, Alcaraz A, Bielsa O, Alvarez Vijande R, Carretero P: Colesteatoma de la pelvis renal en un riñón en herradura. Acta Urol Esp 1991;14:143–145.
8.
Dische MR, Johnston R: Teratoma in horseshoe kidneys. Urology 1979;13:435–438.
9.
Klimberg I, Epstein H, Wajsman Z: Oncocytoma in a horseshoe kidney. J Urol 1985;135:1002–1004.
10.
Torrubia Moreno FJ, Murillo Mirat J, Caballero Gomez M, Asuar Aydillo S: Adenocarcinoma renal en el istmo de un riñón en herradura. Arch Esp Urol 1993;46:43–46.
11.
Eres Saez FJ, Gonzalvo Perez V, Colomer Gonzalez F, Illueca Ferrer E, Zaragoza Orts J: Hipernefroma en el istmo de riñón en herradura. Act Urol Esp 1991;15:384–386.
12.
Vazquez Blanc S, Calahorra Fernandez L, Rodriguez Antolin A, Garcia Luzon A, Carrero Lopez V, Pamplona Casamayor M, et al: Patología tumoral en el riñón en herradura. Acta Urol Esp 1994;18:764–767.
13.
Murphy DM, Zincke H, Furlow WL: Management of high grade transitional cell cancer of the upper urinary tract. J Urol 1981;125:25–29.
14.
Gay BB, Dawes RK, Atkinson GO, Ball TI: Wilms tumor in horseshoe kidneys: Radiologic diagnosis. Radiology 1983;146:693–697.
15.
Riccardi VM, Hittner HM, Francke U, Yunis JJ, Ledbetter D, Borges W: The aniridia-Wilms tumor association: The critical role of chromosome band 11p13. Cancer Genet 1980;2:131.
16.
Pila Perez R, Medrano Lopez L, Ochoa Undargarain O, Pila Pelaez R, Ravelo Gutierrez O: Hipernefroma en el riñón en herradura. Arch Esp Urol 1993;10:919–920.
17.
Domenech-Mateu JM, Gonzales-Compta X: Horshoe kidney: A new theory on its embyogenesis based on the study of a 16-mm human embyo. Anat Rec 1988;222:408.
1998
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.