Experimental surgery in 7 rats was used to investigate the possibility of trigonal urothelium overgrowth into a segment of bowel which had its own mucosa removed. After subtotal cystectomy the intestinal mucosa from the cecum was completely stripped away, and the cecum was then anastomosed to the remainder of the bladder. Urothelial overgrowth of the bowel surface was evident one (3 animals) and two months (4 animals) after the initial procedure.

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