The distribution of ferritin in the kidney and renal tumors was studied using a polyclonal anti-ferritin antiserum and immunocytochemical techniques. Ten fetal kidneys, 5 adult kidneys and 56 renal tumours were studied. Ferritin first appears in the maturing fetal nephron where it is confined to the proximal tubule. In the adult kidney ferritin is also restricted to the proximal tubule. Ferritin was not seen in 18 nephroblastomas nor in 4 renal sarcomas, but 14 of 26 renal cell carcinomas and 5 of 8 renal oncocytomas contained ferritin. The relationship between the expression of ferritin and tumour differentiation is discussed.

Keywords:
Ferritin, Kidney, Embryology, Neoplasms
This content is only available via PDF.
1987
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.