...Jun Yang; Meng-Jie Dong; Qin Xu Graves’ disease Pretibial myxedema Radioiodine Pretibial myxedema (PTM) is an uncommon autoimmune manifestation of Graves’s disease. It is commonly associated with ophthalmopathy and typically localized in the pretibial region [ 1 ]. It is speculated...

...Ola Lindgren; Pernilla Asp; Anna Sundlöv; Jan Tennvall; Bushra Shahida; Tereza Planck; Peter Åsman; Mikael Lantz Background: In Graves’ disease (GD), immunocompetent cells infiltrate thyroid tissue with release of TSH-receptor antibodies (TRAb), and radioiodine treatment is known to elicit...

... should be treated with thyroidectomy or radioiodine. Mixed/indefinite forms of AIT are treated with thionamides. Oral glucocorticoids can be added from the beginning if a precise diagnosis is uncertain, or after a few weeks if response to thionamides alone is poor. The decision to continue or to stop...

...Nicholas S. Andresen; John M. Buatti; Hamed H. Tewfik; Nitin A. Pagedar; Carryn M. Anderson; John M. Watkins Management recommendations for differentiated thyroid cancer are evolving. Total thyroidectomy is the backbone of curative-intent therapy, with radioiodine ablation (RAI) of the thyroid...

... standard. Results: Of the 67 patients, 57 (85%) had radioiodine avid disease and 10 (15%) demonstrated non-radioiodine avid disease. Overall, post-therapy 131 I-SPECT/CT downstaged lymph node staging in 10 patients and upstaged it in 4 patients. This translated into a change of management for 9/57 (16...

... common sites of distant metastasis are to the lungs and bones. Objective: A case is presented to demonstrate the unusual presentation of follicular cancer with synchronous digital (distal phalanx of the little finger) and choroidal metastasis that was responsive to radioiodine treatment. Case Report...

...C. Daumerie; A. Boschi; P. Perros The pathogenesis of Graves’ orbitopathy (GO) remains unknown. The hypothesis of a causal relationship between autoimmunity against the TSH receptor (TSHR) and GO is supported by clinical studies. Radioiodine treatment is associated with worsening or new onset of GO...

... to become pregnant. Thyrotropin receptor antibodies remain elevated following radioiodine therapy, so medical or surgical treatment may be preferred to avoid fetal or neonatal hyperthyroidism. A TSH level <2.5 mIU/l must be achieved in women receiving LT 4 before conception. The patient should...