...Eddy Rijntjes; Philip Moritz Scholz; Govindasamy Mugesh; Josef Köhrle The thioamide anti-thyroid drugs methimazole (MMI) and propylthiouracil (PTU) play a pivotal role in the treatment of hyperthyroidism. MMI exerts its effect via inhibiting one of the key enzymes involved in synthesis of thyroid...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Deiodinase Thyroxine Triiodothyronine Thiols Thyroid-stimulating hormone Illness Propylthiouracil Selenium Selenocysteine Iodine deficiency Pregnancy...

...Peter N. Taylor; Bijay Vaidya Introduction: Hyperthyroidism in pregnancy is a serious condition and its management is complex. Whilst carbimazole/methimazole (CBZ/MMI) and propylthiouracil (PTU) have similar efficacies in controlling hyperthyroidism, their risk of side effects such as major...

...Spiros Karras; Gerasimos E. Krassas The aim of this communication is to provide information regarding the use of antithyroid drugs (ATD) during lactation. Three ATD are used today: propylthiouracil (PTU), methimazole (MMI) and carbimazole (CMZ). The latter is a prodrug which is bioactivated to MMI...

... antibodies. She was started on a reducing regime of propylthiouracil (PTU). At week 20 in pregnancy, she became jaundiced. Initial bloods revealed: bilirubin 91 µmol/l, alanine aminotransferase 1,796 IU/l, alkaline phosphatase 200 IU/l, international normalized ratio 1.2, and albumin 33 g/l. A presumptive...