...Suvi Turunen; Marja Vääräsmäki; Maarit Leinonen; Mika Gissler; Tuija Männistö; Eila Suvanto Objective: Thyroid dysfunction affects up to 5–7% of all pregnancies. The rates of thyroid hormone use in nonpregnant population have substantially increased in recent years. The aim of this study...

...). Pregnancy may represent a stimulus to differentiated thyroid cancer (DTC) growth in patients with known structural or biochemical evidence of disease, but data about malignant SO evolution during pregnancy are rare. We present the first reported case of a pregnant patient with malignant SO and biochemical...

... with ATD at any stage during pregnancy. We selected individuals whose data on maternal FT4 level within 4 weeks of their deliveries and cord FT4 level of their infants at the time of delivery were available. Those with multiple pregnancies, iodine or glucocorticoid treatment, and fetal goiter detected...

... review, we touch upon the assessment of maternal thyroid function in pregnancy and how the historical advancements in thyroid function tests parallel with the thyroid function test abnormalities described. Furthermore, we discuss how the scientific focus has evolved and how the field could turn in view...

... such as age at menarche/menopause, reproductive span, number of pregnancies/childbirths/abortions, investigations for infertility, and years on oral contraceptives. We adjusted for possible confounders such as alcohol intake, smoking, co-morbidity, and education. Age was studied as a potential effect measure...

...Roberto Negro; Roberto Attanasio; Enrico Papini; Rinaldo Guglielmi; Franco Grimaldi; Vincenzo Toscano; Dan Alexandru Niculescu; Diana Loreta Paun; Catalina Poiana Objectives: Pregnancy induces changes in thyroid function, and thyroid dysfunction during gestation is associated with adverse outcomes...

... pmol/L for fT 4 in consecutive trimesters of pregnancy. Reference intervals for pregnant women when compared to the general population showed a lower concentration of TSH in every trimester of pregnancy and lower fT 4 in the 2nd and 3rd trimesters. Conclusions: Using appropriate trimester-specific...

... increased over the pregnancy trimesters from 1.57 ± 1.2 (first) to 1.68 ± 1.0 (second) and 2.02 ± 1.2 mU/l (third; p < 0.001), and serum-free thyroxine (fT 4 ) decreased from 1.22 ± 0.34 (first) to 1.01 ± 0.21 (second) and 0.96 ± 0.2 ng/ml (third; p < 0.05). Serum Tg levels did not change...

... of subclinical autoimmune hypothyroidism, and about 40% had suggested Se use for patients with AIT who were planning pregnancy or already pregnant. About one fourth of the respondents had used Se for mild Graves' orbitopathy. Regarding the suggested daily dosage of Se, 60% of the respondents answered 100-200 µg...

...Eftychia Koukkou; Ioannis Ilias; Irene Mamalis; Georgios G. Adonakis; Kostas B. Markou Objective: To assess the reliability of thyroglobulin (Tg) as a marker of iodine status during pregnancy. Design: 299 women aged 30.5 ± 4.8 years (mean ± SD) were studied. Methods: In every subject, we measured...

... frequently for radioactive therapy. If Graves' orbitopathy occurs, orbit CT/MRI scans are more often obtained in Italy and the EU than in the USA. In case of planned pregnancy in 6-12 months, surgery is more frequently suggested in Italy than in the EU and USA. Propylthiouracil is generally preferred to MMI...

...Stine Linding Andersen; Peter Laurberg Iodine requirements are increased during pregnancy, predominantly caused by an increase in renal iodide clearance and in the use of iodine for thyroid hormone production. Because iodine deficiency (ID) in pregnancy may be associated with neurodevelopmental...

...Stine Linding Andersen; Jørn Olsen; Chun Sen Wu; Peter Laurberg Objectives: Pregnancy loss in women suffering from hyperthyroidism has been described in case reports, but the risk of pregnancy loss caused by maternal hyperthyroidism in a population is unknown. We aimed to evaluate the association...

...Stine Linding Andersen; Louise Kolding Sørensen; Anne Krejbjerg; Margrethe Møller; Peter Laurberg Objectives: Median urinary iodine concentration (UIC) is the recommended method to evaluate iodine status in pregnancy, but several factors may challenge the interpretation of the results. We evaluated...

...John Lazarus; Rosalind S. Brown; Chantal Daumerie; Alicja Hubalewska-Dydejczyk; Roberto Negro; Bijay Vaidya This guideline has been produced as the official statement of the European Thyroid Association guideline committee. Subclinical hypothyroidism (SCH) in pregnancy is defined as a thyroid...

...R. Burns; C. O'Herlihy; P.P.A. Smyth Background: Maintenance of adequate iodide supply to the developing fetus is dependent not only on maternal dietary iodine intake but also on placental iodide transport. The objective of this study was to examine the effects of different pregnancy-associated...

...Françoise Brucker-Davis; Patricia Panaïa-Ferrari; Jocelyn Gal; Patrick Fénichel; Sylvie Hiéronimus Objectives: The aim of the study was to determine the evolution of thyroid tests throughout pregnancy and postpartum in healthy women with and without iodine supplementation. Methods...

...Stine Linding Andersen; Jørn Olsen; Chun Sen Wu; Peter Laurberg Objectives: Maternal hyper- and hypothyroidism have been associated with increased risk of adverse pregnancy outcomes, but studies have led to inconsistent results. We aimed to identify children born to mothers with a hospital-recorded...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Deiodinase Thyroxine Triiodothyronine Thiols Thyroid-stimulating hormone Illness Propylthiouracil Selenium Selenocysteine Iodine deficiency Pregnancy...

...Sylvie Hiéronimus; Patricia Ferrari; Jocelyn Gal; Frédéric Berthier; Stéphane Azoulay; André Bongain; Patrick Fénichel; Françoise Brucker-Davis Objective: To assess the impact on cord blood (CB) thyroglobulin (Tg) of early iodine supplementation during pregnancy. Methods: A total of 111 healthy...