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Keywords: Mouse model
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Journal Articles
Establishment of an Effective Radioiodide Thyroid Ablation Protocol in Mice
Available to PurchaseKathrin A. Schmohl, Andrea M. Müller, Nathalie Schwenk, Kerstin Knoop, Eddy Rijntjes, Josef Köhrle, Heike Heuer, Peter Bartenstein, Burkhard Göke, Peter J. Nelson, Christine Spitzweg
Journal:
European Thyroid Journal
Eur Thyroid J (2015) 4 (Suppl. 1): 74–80.
Published Online: 23 May 2015
... an effective method to generate a thyroid-ablated mouse model that allows the application of the sodium iodide symporter (NIS) as a reporter gene without interference with thyroidal NIS. We tested a range of 131 I doses with and without prestimulation of thyroidal radioiodide uptake by a low-iodine diet...