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Keywords: Type I interleukin-1 receptor
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Eur Surg Res (2011) 47 (4): 274–283.
Published Online: 10 November 2011
...) activation. In contrast, AHCC-SF inhibited the upregulation of type I interleukin-1 receptor (IL-1RI) through the inhibition of Akt phosphorylation. Transfection experiments with iNOS promoter-luciferase constructs revealed that AHCC-SF reduced the levels of iNOS mRNA at both promoter transactivation...