.... The aim of this study was to examine whether complement component 3 is involved in the generation of NETs in AP. Methods: AP was induced in wild-type and C3-deficient mice by retrograde infusion of taurocholate into the pancreatic duct. Blood, lung, and pancreas tissue were collected and MPO activity...

... determined pancreatic weight and pancreatic contents of protein and DNA. We also stained pancreatic sections by immunohistochemistry to show the proliferating cells that either expressed the proliferating cell nuclear antigen or were labeled with 5-bromo-2′-deoxyuridine. As a result, the pancreases...

...Hamidreza Fonouni; Morva Tahmasbi Rad; Majid Esmaeilzadeh; Mohammad Golriz; Ali Majlesara; Arianeb Mehrabi Background: The incidence of diabetes has been steadily increasing. The only curative option for diabetes is pancreas transplantation (PTx). Porcine models are valuable because...

...P.-J. Blind; J. Kral; W. Wang; I. Kralova; P. Abrahamsson; G. Johansson; O. Winsö Background: Ischemic injury to the pancreas occurs in various clinical conditions. A method for online monitoring of pathophysiological events in pancreatic parenchyma is missing. Aims: To assess the timing...

... pancreas/kidney transplantation (PKTx) in detail. Materials and Methods: Donor rats underwent en bloc pancreatectomy and nephrectomy. Revascularization was performed using the aorta with the superior mesenteric artery and the inferior vena cava with the portal vein. Exocrine drainage of the pancreas took...

...E. Zoucas; C. Nilsson; P. Alm; I. Ihse Autonomic nerves have been implicated in the regulation of endocrine and exocrine pancreatic secretion. The purpose of the present study was, therefore, to develop a simple, reproducible technique for selective sympathetic denervation of the rat pancreas...

.... Pancreas Islet transplantation Canine islet isolation Original Papers Eur Surg Res 1990;22:1 -7 © 1990 S. Karger AG. Basel 0014-312X/90/0221-0001S2.75/0 Canine Pancreatic Islet Transplantation: A Comparison of Two Isolation Techniques' J.A. van der Vlietb, D.B. Kaufmana. R.M. Melochea, L.G. van der H...

...J.M. Grönroos Recently we indicated that pancreatic secretory stimulation with pancreozymin superimposed on chronic alcohol intake increases the tissue necrosis in rat pancreas caused by intraductal bile salt administration, and proposed a new theory of the pathogenesis of acute alcoholic...

...J.P.A.M. Vroemen; W.A. Buurman; C.J. van der Linden; R. Visser; K.P.M. Heirwegh; G. Kootstra In previous research into hepatocyte transplantation (HTX) the spleen was the preferred acceptor organ for isolated donor hepatocytes. In this study the pancreas was tested as an acceptor organ for HTX. HTX...

... tissue of the pig and human pancreas. However, neither endocrine cells in Langerhans’ islets nor acinar or ductal cells do express the Ia antigen. Ia-antigen Pancreas © 1984 S. Karger AG, Basel 1984 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... acids. In the exocrine pancreas there was a decreased content of digestive enzymes, especially of amylase, while the secretion of enzymes studied in vitro was reduced. In the ileum left in one piece, the specific activities of maltase and sucrase increased significantly while aminopeptidase...

... on the stimulation of exocrine pancreas through secretin. 10 05 1977 19 09 1977 16 4 2008 Cholecystokinin-pancreozymin Diazoxide Insulin Pancreas Secretin © 1978 S. Karger AG, Basel 1978 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

...T. Monclair; J. Johannesen; S. Aune This study is the first attempt to apply the heat-accumulation technique for metabolic studies to the pancreas. The initial temperature rise during arterial occlusion was measured with thermocouples sutured into the pancreas of seven anaesthetized pigs...

... < 0.05). After reperfusion, plasma lipase in the L -arginine-treated animals was significantly lower compared to IR and sodium nitroprusside (p < 0.05). Conclusions: The administration of both endogenous and exogenous NO donors is protective in IRI of the rat pancreas which can be seen...

... immunosuppression. Since total pancreatic graft in man is metabolically more proficient than islet graft, we attempted tolerance induction for total vascularized pancreas transplantation in diabetic BN recipient rats by an intrathymic bone marrow cell (BMC) injection from Lewis donor rats, associated...

... optical coupling between laser Doppler probes and rodent tissues, and (3) a simple technique of inducing intestinal ischaemia-reperfusion while continuously monitoring the microvascular perfusion in both pancreas and intestine. The utility of the model is demonstrated in a pilot study that showed...

... aDepartment of Surgery and Diabetic Research Unit, and bDepartment of Pathology, Laënnec Hospital, and cLaboratory of Physiopathology of Nutrition, CNRS ESA 7059, University Denis Diderot-Paris 7, Paris, France Key Words Diabetes W Pancreas W Transplantation W Portal drainage Abstract A perfect metabolic...

... C received octreotide (2.5 μg/kg subcutaneously), and group D received BBS and octreotide. All substances were injected three times a day until sacrifice after 28 days. BBS increased pancreas weight (p = 0.003) and DNA synthesis (p < 0.001), as measured by a bromodeoxyuridine nuclear-labeling...