... tissues. Upscaling from the small animal AV loop model into a preclinical large animal model could pave the way for the first successful attempt in clinical application. Key Messages: The AV loop model is a powerful tool for the generation of different axially vascularized replacement tissues. Due...

... is formed by an understanding of the mechanisms of PVO-induced liver regeneration, mainly obtained from animal studies. The aim of this review is to give a comprehensive overview of the relevant animal models of PVO and to discuss the main characteristics of triggered liver regeneration, including...

...H.C. Pommergaard; J. Rosenberg; C. Schumacher-Petersen; M.P. Achiam Background/Aims: Animal models are valuable for studying pathogenic factors and preventive measures for colon anastomotic leakage. The suitability of the species as models varies greatly; however, no consensus exists on which...

... regeneration in the host liver in patients with liver failure treated by auxiliary liver grafting, leading to the question of whether the development of an acute or acute-upon-chronic liver failure in a large-animal model is useful to test the effect of injecting serum extracts of liver hepatotrophic...

...J. Tang; Y. Wang; W. Hang; W. Fu; Z. Jing Background/Aims: Stanford type A and type B aortic dissections are anatomically distinct. Few animal models appropriately mimic human aortic dissection in the clinical setting. We developed animal models that mimicked uncontrollable Stanford type B aortic...

... strategies should be developed. We present a new animal model for the evaluation of such strategies. Methods: In a pig model (n = 9), anterolateral thoracotomy was performed for exposure of the left ventricle. mVSDs were created under two- and three-dimensional echocardiography with a 7.5-mm sharp punch...

...Nathan Lawrentschuk; Angela Rigopoulos; Fook-Thean Lee; Ian D. Davis; Andrew M. Scott; Damien M. Bolton Introduction: The growth of human tumours under the renal capsule in animal models has been performed in the past. However, the use of modern surgical equipment has not always been translated...