...H. Konno; A.F.M. Matin; Y. Maruo; S. Nakamura; S. Baba Liposomes are useful drug carriers. In this study, adenosine triphosphate (ATP) was entrapped in liposomes (Lip-ATP). Anesthetized rats were given Lip-ATP (5 mg/kg as ATP), free ATP (5 mg/kg) or saline (control group) during stabilization...

... of the proper hepatic artery and portal branches. The effect of allopurinol (ALL) on metabolism of ATP and HXA was studied before, during and after a 60-min normothermic ischemic insult. Liver cell concentration of HXA in the group treated with ALL increased during ischemia and decreased rapidly during...

...J.F. Ngala Kenda; B. de Hemptinne; L. Lambotte Changes in hepatic ATP energy charge (EC = ATP + 0.5 ADP/ATP + ADP AMP) as an expression of metabolic overload and oxidative phosphorylation were studied conjointly with DNA synthesis after partial hepatectomy (PH) in the male rat. ATP and EC showed...

.... The corresponding value in vitro was 40 %. Alterations of protein synthesis in vitro during and after a period of liver ischemia were similar to changes of ATP in liver tissue. Thus, changes of protein synthesis noticed in vitro reflected alterations of protein synthesis in vivo and changes of energy level in liver...

... and the subendocardial layer of the left ventricular free wall occurred. No differences between the three operation techniques could be observed on the basis of the above-mentioned parameters. Myocardial ATP and glycogen contents were decreased in postischaemic tissue in both the normothermic and hypothermic...

... hypotension and resulted in a much lesser increase in plasma allantoin. The pancreatic, liver and duodenal adenosine triphosphate (ATP) and total adenine nucleotides of untreated dogs were severely reduced, while those of allopurinol-pretreated dogs were essentially normal 2 h following reinfusion...

...M. Romanus; H. Haljamäe The effects of pressure-induced ischemia on energy metabolism, measured as ATP and glucose content, is studied in hamster cheek pouch. Metabolic deterioration during ischemia is studied and after 2 h the glucose content was significantly reduced but not the ATP content...

..., decrease in blood pressure and death 3–4 h after the replacement of the intestine, was used. During the exteriorization period and after the return of the intestine repeated skeletal muscle biopsies were taken for enzymatic fluorometric analyses of ATP, phosphocreatine, G-6-P, glucose and lactate...

... a maximum of 50 h after hepatectomy, and the liver regeneration rate, the proportion of PCNA-positive cells and the ATP volume in the remnant tissues were examined. Results: In the HBOT group, the liver regeneration rate at 36 h and 50 h after operation and the proportion of PCNA positive cells at 8 h...

...K. Chijiiwa; S. Saiki; H. Noshiro; N. Kameoka; K. Nakano; M. Tanaka Clinically portal vein embolization (PVE) is presently preferred to extended hepatectomy. Nevertheless, its effect on hepatic adenosine triphosphate (ATP) and energy charge levels, which are essential for organ viability, has been...