A complex fluid containing electrolytes, metabolic substrates, enzyme cofactors, and hydrogen acceptors in concentrations similar to those of the renal cytoplasm was successfully used in preserving kidneys up to 72 h withσut artificial perfusion. The results of electron optic investigations presented in this paper demonstrate that some changes in the renal ultrastructure and enzyme reactions occur suggesting a simple low-grade hyperhydration of the renal cells and that this fluid has no irreversible, deleterious effects on these cells.

Keywords:
Kidney preservation, ‘Cytoplasmic’ solution, Hypothermia, Transplantation
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© 1973 S. Karger AG, Basel
1973
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