This study compared the physical characteristics of Vivostat® patient-derived sealant with two conventional fibrin sealants, Tissucol® and Beriplast®. Vivostat sealant exhibited greater elasticity without compromising tensile strength. Vivostat sealant polymerised at low temperatures (4 and 25°C) or at high temperature (70°C) exhibited similar viscoelastic properties as when polymerised at normal physiological temperature (37°C). Vivostat fibrin I solution can be stored at room temperature for up to 8 h without affecting the mechanical properties of the derived sealant. These physical characteristics of Vivostat patient-derived sealant suggest that it may have suitable stability and performance characteristics for use in a wide range of surgical procedures.

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