...Xiaoni Yang; Chao Chen; Aishuai Wang; Changsheng Li; Guangqing Cheng Background: Over the past decades, marked progress has been made in detecting vascular dementia (VD) both through maturation of diagnostic concepts and advances in brain imaging, especially MRI. We summarized the imaging, genetic...

.... On postmortem 7.0-tesla MRI, however, CoMIs of different size are easily detected. Summary: The present MRI study investigates 84 postmortem brains with different neurodegenerative diseases and vascular dementia (VaD) for their topographic distribution and the prevalence of CoMIs. The mean numbers of CoMIs were...

...Yu-dan Chen; Juan Zhang; Yue Wang; Jun-liang Yuan; Wen-li Hu Background/Aims: The objective of this study was to determine whether treatment with acetylcholinesterase inhibitors would provide cognitive benefit for patients with vascular dementia. Methods: Studies in patients with vascular dementia...

... (ADL) in a large, well-defined cohort of patients with mild-to-moderate dementia (either Alzheimer’s disease or subcortical vascular dementia) were investigated. A total of 289 patients were divided into three groups (140 mild, 99 moderate, and 50 severe) depending on the degree of white matter changes...

...G. Sorrentino; R. Migliaccio; V. Bonavita Vascular dementia (VaD), rather than being considered as a univocal nosological entity, should be regarded as a heterogeneous clinical entity which differs in clinical-pathological phenotype as well as in pathophysiological mechanisms, but shares...

.... Vascular dementia Lacunes Dementia and lacunes Editorial Eur Neurol 1995;35:187-192 Carlo Loeb Department of Neurology, University of Genova, Italy Dementia due to Lacunar Infarctions: A Misnomer or a Clinical Entity? Key Words Vascular dementia Lacunes Dementia and lacunes Abstract The following...

...Reinhold Schmidt MRI scans of 27 patients with probable Alzheimer’s disease (mean age 68.2 years), 31 patients with vascular dementia (mean age 69.9 years) and 18 normal controls (mean age 66.3 years) were compared to evaluate possible distinguishing parenchymal abnormalities among these groups...

... and endocrine derangements. The differential diagnosis between degenerative and vascular dementia needs laboratory tests such as CSF, EEG, Somatosensory Evoked Potentials, CT (which constitutes a major role in a modified ischemic score) and MRI. The three final diagnostic labels are possible, probable...

...Philip Scheltens; Willem A. van Gool Dementia is one of the most common organic mental syndromes, usually caused by Alzheimer''s disease (AD) or vascular dementia (VD) or both. Regarding AD we review the state of the art of the cholinergic approach and discuss some future options regarding...

...) and vascular dementia (VaD). The aim of this study was to explore cerebral hemodynamics by transcranial Doppler in VaD and AD, compared with age-matched control subjects. Methods: Transcranial Doppler was investigated in all patients in the basal condition. Cerebral vasoreactivity to hyper- and hypocapnia...

...-brain barrier (BBB) function] and other CT changes. The study included 85 patients, average age 71 ± 8, with Alzheimer’s disease (n = 56) and vascular dementia (n = 29), who underwent CT (Siemens Somatome DR 1) of the brain. They were inpatients in a psychiatric department specialized in dementia...

... or cerebral infarct or cerebral hemorrhage or cerebrovascular disease or transient ischemic attack (TIA)’. WMC, as defined radiologically, are present in up to 44% of patients with stroke or TIA and in 50% of patients with vascular dementia. WMC are more frequent in patients with lacunar infarcts, deep...

...Gabriel Gold; Panteleimon Giannakopoulos; Constantin Bouras Alzheimer’s disease (AD) and vascular dementia (VaD) are the two most common causes of dementia, and much effort has been devoted to their differential diagnosis. However, current epidemiological, clinical and neuropathological evidence...