...M.I. Botez; Lucia Pedraza; Thérèse Botez-Marquard; Jean-Lorrain Vèzina; Robert Elie We measured simple visual and auditory reaction time (RT) and movement time (MT) in 32 patients with olivopontocerebellar atrophy (OPCA) in comparison to 32 control subjects. In addition, we followed 2 approaches...

... in sporadic cerebelloolivary atrophy (Holmes, n = 9) and sporadic olivopontocerebellar atrophy (OPCA, n = 6). The uptake in the pons was decreased in OPCA. The decrease of the uptake in the cerebellum and the pons was associated with clinical severity in OPCA. Our results show that semiquantitative SPECT...

...Thèrése Botez-Marquard; M.I. Botez Fifteen patients with Friedreich’s ataxia (FA) and 15 others with olivopontocerebellar atrophy (OPCA) were evaluated with a comprehensive neuropsychological battery of tests. They were pair-matched with normal controls for age, sex and education. Depressed...

...M. Mondelli; G. Ciacci; S. Parlanti; C. Scarpini; G. Vignocchi; A. Rossi We report the electrophysiological findings of the central and peripheral somatosensory pathways in 20 patients with olivopontocerebellar atrophy. Changes in sensory action potentials of the median nerve were observed in 14...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Olivopontocerebellar atrophy Lecithin Choline Eur. Neurol. 24: 414-421 (1985) © 1985 S...

...Gyeong-Moon Kim; Sang Eun Kim; Won Yong Lee We investigated whether the dopamine (DA) transporter system is impaired in sporadic olivopontocerebellar atrophy (sOPCA) patients without clinical parkinsonism using the DA transporter radiotracer [ 123 I]β-CIT [2β-carboxymethoxy-3β-(4-iodophenyl)tropane...

...M.I. Botez; T. Botez-Marquard; R. Elie; N. Le Marec; O.L. Pedraza; R. Lalonde The efficacy of amantadine, a dopamine-releasing agent and antagonist of the N-methyl- D -aspartate glutamate receptor, was evaluated in patients with olivopontocerebellar atrophy. By contrast to an untreated control...