...Sophie Bayard; Cindy Lebrun; Alexia Arifi-Rossignol; Christian Geny; Marie-Christine Gély-Nargeot; Annemarie I. Luik Background: Insomnia is a highly common sleep disorder in patients with Parkinson’s disease (PD). Yet, no screening questionnaires following the Diagnostic and Statistical Manual-5...

... Insomnia Restless legs syndrome (RLS) consists of an inescapable urge to move the limbs during evening hours and periods of rest; table 1 depicts the four essential diagnostic criteria proposed during the National Institutes of Health Consensus Workshop [ 1,2 ]. Often distressing, these symptoms...

... to in the content or advertisements. Sleep disorders Epidemiology Insomnia Periodic limb movements of sleep The prevalence of restless legs syndrome (RLS) has been established to be approximately 10% in the Caucasian populations of Western Europe and North America [ 1,2,3,4,5 ]. It has been...

... clinical studies dealing with sleep abnormalities in PD and present clinical recommendations. Previous studies describing insomnia, excessive daytime sleepiness, narcolepsy-like episodes, circadian changes, sleep-disordered breathing, rapid eye movement sleep behavior disorder, vivid dreams and restless...

...Dietrich Schneider-Helmert Impaired daytime functions are a significant part of chronic insomnia besides sleep disturbance. Therefore, the effects of intermediate-term delta-sleep-inducing peptide (DSIP) administration on sleep and daytime performance were investigated in 14 middle-aged chronic...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. DSIP Sleep disturbance Insomnia Narcolepsy ...

...Dietrich Schneider-Helmert This paper summarizes different investigations into effects of delta sleep-inducing peptide (DSIP) injections on insomnia. Two different studies showed improvement of sleep following single injections of 25 nmol/kg b.w. before sleep. Repeated administrations indicated...

...H.E. Kaeser In an open study 7 patients with severe insomnia were treated by a series of 10 injections with the delta-sleep-inducing peptide (DSIP). In all but 1 case sleep was normalized for follow-up periods of 3–7 months. The mood and performance during the daytime improved as well. A problem...

...Jean-Michel Gaillard The aim of this paper is to examine if a disturbance of slow-wave sleep may partly account for the imbalance between waking and sleep observed in insomnia. 40 normal subjects and 40 insomniacs were recorded in the laboratory. No direct interregulation appeared between total...

...-onset RLS). Sensory disturbances were painful in 56% of patients and felt in legs (98%), arms (35%), and ‘internally’ (45%). Motor disturbances included ‘dyskinesias while awake’ (36%). Insomnia (58%) was commoner than hypersomnia (24%). In 67% of the patients, no etiology of RLS was found (idiopathic...