...J.-C. Roches; H.R. Zumstein; A. Fässler; G. Scollo-Lavizzari; L. Hösli The action of intravenously injected taurine, glycine and GABA has been tested on convulsions induced by strychnine using electroencephalographic and electromyographic recordings. The dose of strychnine necessary to produce...

...T. Caraceni; P. Giovannini; F. Girotti; G. Avanzini Dipropylacetic acid (DPA), γ-aminobutyric aicd (GABA), physostigmine, CB 154 and butyrophenones were administered to 26 patients affected by Huntington’s chorea. The evaluation of the pharmacologic activity of the different drugs was determined...

...E. Schneider; B. Ziegler; H. Maxion The effects of di-n-propylacetic acid (DPA) on sleep, for some years used as an anticonvulsive drug, has been investigated in 11 healthy volunteers using all-night sleep EEG recordings. DPA acts by an enhancement of the gamma-aminobutyric acid (GABA) level...

...U.K. Rinne; H. Laaksonen; P. Riekkinen; V. Sonninen The activity of glutamic acid decarboxylase (GAD), the enzyme involved in formation of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), was studied in autopsy brain samples from six parkinsonian patients and 13 controls...

... of sleep stages and electromyographic changes was obtained. A new benzodiazepine (Ro 054023) was tried after L-dopa. A possible imbalance between a catecholaminergic and a GABA-ergic system in the Stiffman syndrome is hypothesized. 12 01 1973 7 03 1973 23 1 2008 © 1973 S. Karger AG...

...G. Scollo-Lavizzari; F. Corbat Depakine® sodium di-n-propylacetate is a new anti-epileptic drug. Its action may be related to inhibition of GABA-transaminase. We report our results with Depakine treatment in 33 patients with Petit Mal, myoclonic Petit Mal, Grand Mal and focal epilepsy. We can...

... of improving the cerebellar signs in cases of CCA, after single doses and after continued administration of the drug during 4 weeks. GABAergic enhancement or supplementation could play an important role in the treatment of diseases of the cerebellar cortex associated with a deficit of GABA. 2 10 2003...

... Effects of Gabapentin on the Different Components of Peripheral and Central Neuropathic Pain Syndromes: A Pilot Study OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Key Words Neuropathic pain Gabapentin GABA Allodynia Hyperalgesia...