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Keywords: DSIP
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Journal Articles
Eur Neurol (1987) 27 (2): 120–129.
Published Online: 05 February 2008
...Dietrich Schneider-Helmert Impaired daytime functions are a significant part of chronic insomnia besides sleep disturbance. Therefore, the effects of intermediate-term delta-sleep-inducing peptide (DSIP) administration on sleep and daytime performance were investigated in 14 middle-aged chronic...
Journal Articles
Eur Neurol (1986) 25 (6): 448–453.
Published Online: 05 February 2008
...Dietrich Schneider-Helmert The immediate effects of one week of Delta Sleep-Inducing Peptide (DSIP) administration (6 X 30 nmol/kg b.w., i.v.) and late effects after a follow-up period of one week were investigated in a sleep laboratory study. The population of 18 chronic psychophysiological...
Journal Articles
Eur Neurol (1986) 25 (Suppl. 2): 154–157.
Published Online: 05 February 2008
...D. Schneider-Helmert The effects of DSIP on night sleep and on waking functions are demonstrated in double-blind studies in insomniacs, presenting influences of single dose treatments as well as of repeated injections. Moreover, a single case study describes the efficiency of DSIP on narcolepsy...
Journal Articles
Eur Neurol (1984) 23 (5): 353–357.
Published Online: 31 January 2008
...Dietrich Schneider-Helmert Repeated injections of delta sleep-inducing peptide (DSIP) were given to a 35-year-old male narcoleptic. Effects on wakefulness and sleep were evaluated by self-reports, performance tests, multiple sleep latency test and all-night polysomnography. DSIP reduced...
Journal Articles
Eur Neurol (1984) 23 (5): 364–371.
Published Online: 31 January 2008
...P. Dick; C. Costa; K. Fayolle; M.E. Grandjean; A. Khoshbeen; R. Tissot The hypothesis for this therapeutic use of delta sleep-inducing peptide (DSIP) was based on several animal studies conducted by Tissot. He showed that morphine, alcohol, pentobarbital as well as DSIP, when injected directly...
Journal Articles
Eur Neurol (1984) 23 (5): 358–363.
Published Online: 31 January 2008
...Dietrich Schneider-Helmert This paper summarizes different investigations into effects of delta sleep-inducing peptide (DSIP) injections on insomnia. Two different studies showed improvement of sleep following single injections of 25 nmol/kg b.w. before sleep. Repeated administrations indicated...
Journal Articles
Journal Articles
Eur Neurol (1984) 23 (5): 386–388.
Published Online: 31 January 2008
...H.E. Kaeser In an open study 7 patients with severe insomnia were treated by a series of 10 injections with the delta-sleep-inducing peptide (DSIP). In all but 1 case sleep was normalized for follow-up periods of 3–7 months. The mood and performance during the daytime improved as well. A problem...
Journal Articles
Eur Neurol (1984) 23 (5): 346–352.
Published Online: 31 January 2008
...R. Scherschlicht; L. Aeppli; P. Polc; W. Haefely The synthetic nonapeptide DSIP was studied in rabbits and cats under normal conditions and under conditions of disturbed sleep. In other experiments, the effect of the oligopeptide on withdrawal jumping provoked by naloxone in morphine-dependent mice...