...Lulu Yao; Jingnian Ni; Mingqing Wei; Ting Li; Ziyi Long; Jing Shi; Jinzhou Tian Introduction: Depression has been associated with cognitive performance, but whether sociodemographic and clinical characteristics might influence this association is not well elaborated. This study aimed to further...

...Yulin Luo; Li Tan; Joseph Therriault; Hua Zhang; Ying Gao; and the Alzheimer’s Disease Neuroimaging Initiative Background: Apolipoprotein E ( APOE ) ε4 is highly associated with mild cognitive impairment (MCI). However, the specific influence of APOE ε4 status on tau pathology and cognitive decline...

...Ji Won Han; Hyunna Lee; Subin Lee; Haejin Kim; Grace Eun Kim; Jong Bin Bae; Seung Wan Suh; Jae Hyoung Kim; Ki Woong Kim Introduction: The irregular shapes of white matter hyperintensities (WMHs) are associated with poor cognitive function, diabetes, or lacunes. However, the association between...

...Ping Qu; Jin-Xia Yu; Gui-Hai Chen Background: Fibromyalgia (FM) is a chronic widespread pain disorder associated with fatigue, tender points, sleep disturbances, and mood disorders. Symptoms associated with FM also include decreased cognitive function in which the neural basis is poorly understood...

...Ozge Arici Duz; Ozlem Saatci; Ece Zeynep Karakulak; Erkingul Birday; Lutfu Hanoglu Background: Multiple Sclerosis (MS) is a neuroinflammatory, neurodegenerative, demyelinating disease that causes cognitive, olfactory, and other neurological dysfunctions. Radiologically Isolated Syndrome (RIS...

...Sjors C.F. van de Weijer; Annelien A. Duits; Bastiaan R. Bloem; Nienke M. de Vries; Roy P.C. Kessels; Sebastian Köhler; Gerrit Tissingh; Mark L. Kuijf Cognitive training (CT) shows modest positive effects on cognitive function in patients with Parkinson’s disease (PD). Gamification may enhance...

...Eloi Magnin; Yoshimasa Sagawa; Thierry Moulin; Pierre Decavel Introduction: Cognitive impairment is frequent in persons with multiple sclerosis (PwMS) and can impact on activities of daily living. The capacity to differentiate real changes from background statistical noise induced by human...

... a cooling vest during a physical training program could increase the cognitive and physical capacities and quality of life in PwMS. Methods: Eighteen PwMS (49.6 ± 8 years; Expanded Disability Status Score 5.0 ± 1.0) were randomly assigned to a cooling or control group. PwMS underwent a 7-week physical...

...Jun-Liang Yuan; Shuang-Kun Wang; Xiao-Juan Guo; Lei-lei Teng; Hua Jiang; Hua Gu; Wen-Li Hu Background: We aimed to explore the relation between the microstructural integrity of white matter using the technique of diffusion tensor imaging (DTI) and changes of cognition in leukoaraiosis (LA). Methods...

...Jessica Burggraaff; Dirk L. Knol; Bernard M.J. Uitdehaag Background/Aims: Appropriate and timely screening instruments that sensitively capture the cognitive functioning of multiple sclerosis (MS) patients are the need of the hour. We evaluated newly derived regression-based norms for the Symbol...

... in flexibility associated with modifications in their driving. Flexibility seems to be affected as the disease progresses. This research opens new avenues in cognitive and driving rehabilitation. [email protected] 12 05 2016 3 08 2016 2 9 2016 © 2016 S. Karger AG, Basel 2016...

...: A total of 146 probable AD patients consented to genetic testing for butyrylcholinesterase and underwent the final efficacy evaluations. Responders were defined as patients with an equal or better score on the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) at 16 weeks compared...

.... THC:CBD oromucosal spray was well tolerated in these studies, with no evidence of effects typically associated with recreational cannabis use. In a subsequent post approval clinical trial, THC:CBD oromucosal spray had no statistically significant effect on cognition and mood compared with placebo...

...Li Feng; Ding Bang Chen; Le Hou; Lin Huan Huang; Shu Yang Lu; Xiu Ling Liang; Xun Hua Li Background: Previous studies have shown cognitive impairment in patients with spinocerebellar ataxia type 3 (SCA3). However, there is a lack of data on Chinese patients with SCA3. Method: We investigated 22...

... available in 2013 and are reviewed. A randomized, placebo controlled long-term follow-up clinical trial with THC:CBD spray versus placebo demonstrated that it was not associated with cognitive decline, depression or significant mood changes after 12 months of treatment. Furthermore, in a prospective...

...Ayhan Koksal; Cahit Keskinkılıc; Mehmet Vedat Sozmen; Ayten Ceyhan Dirican; Fikret Aysal; Yavuz Altunkaynak; Sevim Baybas Aim: In this study, cognitive functions of 9 patients developing parkinsonism due to chronic manganese intoxication by intravenous methcathinone solution were investigated using...

...Carmen Sáez-Zea; Francisco Escamilla-Sevilla; Majed J. Katati; Adolfo Mínguez-Castellanos Background: Subthalamic nucleus deep brain stimulation (STN-DBS) improves motor function in selected patients with Parkinson’s disease (PD) but can be associated with variable changes in cognitive functions...

... and Cognitive Functions [FSMC], Fatigue Severity Scale, and Modified Fatigue Impact Scale), depression (Beck Depression Inventory Fast Screen), cognition (Brief Repeatable Battery of Neuropsychological Tests) and upper and lower extremity functions (Nine-Hole Peg Test and 25-foot walk). Results: Depending...

...C. Lang; C. Reiss; M. Mäurer Immunomodulating therapies may prevent relapses in multiple sclerosis and stabilize neurological status. However, little is known about the influence particularly of newer drugs on cognitive functions. We conducted an open-label prospective study to demonstrate whether...

... the impact of SILs on cognitive functioning following CAS. Methods: The retrospective study separated 131 patients with unilateral carotid stenosis into three groups: medication only, MRI-evaluated CAS and CT-evaluated CAS, and compared the sociodemographic factors, post-CAS images and Mini-Mental State...