Abstract
Protracted epidural pressure (EDP) measurements were carried out in 3 control patients and 4 patients with normal pressure hydrocephalus (3 definite and 1 probable). Simultaneous intraventricular (VFP) and EDP monitoring was carried out over 24 h in one of the controls, one of the patients with normal pressure hydrocephalus and in the patient with probable normal pressure hydrocephalus. Mean night EDP was higher than day EDP in all except one patient with normal pressure hydrocephalus, in whom the mean night/day ratio was 0.92. The mean night/day ratio for all patients was identical in patients and controls, i.e. 1.06. In this study, there was thus no evidence that normal pressure hydrocephalus patients have higher than normal average intracranial pressure by night. A rather continuous moderate increase in intracranial pressure was found in the one patient with probable normal pressure hydrocephalus. Episodes of increased EDP of more than a few minutes duration were found in both patients and controls, more frequently by night than by day.