...C. Denef Critical levels of steroid sex hormones during critical phases of development determine sexual differentiation of brain and pituitary. In rats, sex hormone production and metabolism in the gonads, steroid metabolism in the liver,and metabolism of androgen in target tissues of the brain...

... suppressors of this enzyme: pituitary products (including growth hormone and ACTH) and thyroxine, participate in the regulation of the postnatal development of this enzyme. The developmental pattern of competence of the liver to respond to each hormonal inducer is temporally characteristic for each hormone...

...Anja Reinharz; M. Roth A proteolytic enzyme acting at acidic pH has been partially purified from bovine anterior pituitary. It was found to hydrolyze the artificial substrate, Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-ß-naphthylamide at the Phe-His and the Leu-Leu bonds. This hydrolysis serves as basis...