... oxidation, hepatic ketogenesis and utilization of ketone bodies by extrahepatic tissues during development of the rat are described. Factors involved in the developmental changes in these aspects of lipid metabolism of the rat are discussed. Key Words Development Extrahepatic Ketone bodies Liver (3...

...R.W. Hanson; Linda Fisher; F.J. Ballard; Lea Reshef The activity of phosphoenolpyruvate carboxykinase in the liver of fetal rats can be induced in utero by administration of either glucagon or dibutyryl-cAMP to the fetuses. Both of these compounds cause a rapid rise in enzyme activity,followed...

...C.F. Strittmatter Changes in specific activity levels of disaccharidases in the intestine and of phosphatases in liver and intestine were studied during development of the chick embryo and chick. A diversity of developmental patterns were observed among the various enzymes. However, many...

...A.M. Nemeth In mammals, enzymes subserving special adult liver functions such as amino acid degradation and detoxification are generally absent during most of fetal life, appear near term and increase to adult levels at birth. The change in environment at birth appears to initiate development...

...J.K. Pollak; C.G. Duck-Chong A large number of investigations into changes in rat liver mitochondria and endoplasmic reticulum during development and differentiation have been reviewed in the light of current ideas about the dynamic nature of membranes. Particular attention has been paid...

...R.L. Jacquot; C. Plas; J. Nagel Two physiological maturations of the rat liver are presented in this paper. The ability for glycogen storage depends in vivo on the presence of endogenous circulating glucocorticoids. Similarly, in vitro, primary cultures of fetal hepatocytes store glycogen only...

... Embryo Enzymes Glucuronidation Induction Liver Phenobarbital 1617609 Enzyme 15: 304-317 (1973) Developmental Studies on Some Enzymes Associated with Detoxication G.J. Dutton Department of Biochemistry, Medical Sciences Institute, The University, Dundee Abstract. A definition of detoxication...

...Lauro Galzigna; Valeria Rizzoli; Patrizia Schiappelli; Carlo Moretto; Alberto Bernareggi S-acetyl- and S-phenylacetyl-glutathione derivatives were synthesized by using a new procedure. The derivatives were incubated with rat plasma and red blood cells, and also with cytosol from rat liver, kidney...

...Ichitomo Miwa; Mita Yumiko; Tomiyasu Murata; Jun Okuda; Michiharu Sugiura; Yoshiki Hamada; Taku Chiba Glucokinase, an enzyme that catalyzes the phosphorylation of glucose, constitutes the key regulatory step in glucose metabolism in pancreatic islets and liver. We found that 3-O-methyl-N-acetyl-D...

...Rashid Ali; S.C. Agarwala The effect of normal and irradiated psoralen in vitro and in vivo has been studied on glucose oxidation of brain and liver homogenates. Psoralen per se was found to have no effect on in vitro glucose oxidation of brain, while psoralen irradiated for 0.5,1, 2, 3,and 4 h...

...W.E. Criss Antibody to purified rat liver adenylate kinase isozyme III was prepared in rabbits. The antibody preparation inhibited the activity of liver adenylate kinase III, but did not affect the activity of liver adenylate kinase I, II, or IV. The antibody preparation inhibited the adenylate...

...Helen B. Burch; Oliver H. Lowry; Lucile M. Delaney Three enzymes of glycerol metabolism, glycerol kinase, a-glycero-P dehydrogenase, and a-glycero-P oxidase were measured in rat liver from several days before birth to maturity. Two of the enzymes were also measured in kidney cortex and medulla...

...Janet Thorndike Serine dehydratase activity was determined in the livers of mice at different ages. Enzyme activity was low in fetal liver, increased after birth, and reached its adult level after seven weeks. 11 8 2017 1972 Copyright / Drug Dosage / Disclaimer Copyright: All rights...

...S.M.I. Kazmi; N.Z. Baquer Studies with brain alanine aminotransferase showed higher activity of the enzyme in the soluble fraction of cerebellum. Among the tissues, the liver soluble fraction was the richest source of the enzyme. Alloxan-induced diabetes caused both regional and timedependent...

...Dita Cotariu; Sandra Evans; Jacob L. Zaidman Previous observations that valproic acid (VPA) causes hepatic damage prompted us to investigate the effect of large doses of the drug (0.6, 1.2 and 1.8 mmol/kg/day) on a number of liver enzymes located on different subcellular fractions. In mitochondria...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Xanthine dehydrogenase Liver Kidney Development Dexamethasone Enzyme 35: 70-76 (1986) 1606627 © 1986 S. Karger AG...

...E. Jiménez; P. Morata; M. Montiel; I. Garcia-Chacon; M. Morell The developmental pattern of citrate synthase activity has been studied in the liver and several brain areas of hypothyroid rats during the 4 first weeks of life. While citrate synthase activity in the liver showed a rise during the 2...

...Michael Ball; Patricia Mclean The activities of adenine nucleotide translocase (ANT), Na^+-K^+-ATPase (EC 3.6.1.3) and Mg^2+-ATPase (EC 3.6.1.3) together with mitochondrial marker enzymes, succinic dehydrogenase (EC 1.3.99.1) and glutamate dehydrogenase (EC 1.4.1.2), were measured in liver, kidney...

...Josefa P. Gartia-Ruiz; Maria F. Lobato; Manuel Ros; Francisco J. Moreno The cytosolic P-enolpyruvate carboxykinase activity was measured in mammary gland and liver of animals at all stages of the reproductive cycle. The specific activity of this enzyme was almost absent in the mammary gland...

... In rats bearing a subcutaneously implanted Walker 256 carcinoma an early rise in liver DNA content was followed by a two-fold increase in RNA content between the 6th and 10th day of tumour growth. Total hepatic neutral ribonuclease and its inhibitor were unaffected by tumour growth. No alteration...