... mol/l) is optimal for the liver isoenzyme than for the kidney isoenzyme (0.2 mol/l). Endogenous phosphate supplies the low phosphate requirement in crude liver preparations. Glutaminase Isoenzyme Glutamine 1971 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

...W.E. Knox; H.Z. Kupchik; Louise P. Liu Glutamine synthetase and glutamine concentrations were compared in various rat tissues, in rat liver throughout development and during regeneration, and in transplanted tumors. There was no obvious relationship between the two components in these tissues...

...Carol Franklin; Leon Goldstein Properties of renal phosphate-dependent glutaminase (EC 3.5.1.2), assayed in tissue homogenates, were compared in adult, 2-week-old, and newborn rats. V(max), K(m) glutamine, pH optimum, inhibition by glutamate, activation by phosphate, intracellular distribution...

... zonation is the reciprocal distribution of carbamoylphosphate synthase and glutamine synthase in the liver lobule. The mechanisms underlying the different sublobular gene expressions are not yet settled but may involve the development of hepatic architecture, innervation, blood-borne hormonal and metabolic...

... confluency. The increase of glutaminase activity was independent of the glutamine concentration between 0.2 and 2.0 mmol/1. In contrast, the specific activity of glutamate dehydrogenase was independent both of the glutamine concentration and the growth phase of the cultured cells. These results indicate...