... groups of the renin molecule are essential for enzymic activity. Renin Inhibition Fluorimetry Bioassay Bioassay Hog 1971 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any...

... of a sensitive fluorimetrie assay. The enzyme is similar to cathepsin D. The pentapeptides Z-Pro-Phe-His-Leu-Leu-β-naphthylamide and Z-Leu-Leu-Val-Tyr-Serß-naphthylamide were also attacked, but at a much slower rate. Smaller substrates were not hydrolyzed. The results indicate that the enzyme preferentially...

...D. Depierre; M. Roth A fluorimetrie assay of dipeptidyl carboxypeptidase is described. It involves incubation at 37 °C with the substrate, Z-Phe-His-Leu, and reaction of the dipeptide His-Leu which is released upon enzymatic hydrolysis, with o-phthalaldchyde to yield a fluorescent compound...