...D.C. Turner; H.M. Eppenberger Tissue specific isoenzyme distributions of creatine kinase and aldolase in muscle and brain of chicken and rat show similarities suggesting coordinate regulation of these two enzymes. In vitro studies of chick skeletal muscle differentiation provide evidence...

...Elena Tzvetanova We studied the isoenzymes of creatine kinase in the skeletal muscles of 63 patients with various neuromuscular diseases, of 30 human fetuses and of normal subjects (controls). In the muscle tissue of the control group the MM isoenzyme alone could be found; only 2 normals had traces...

...Ze-Feng Wang; Yi-Kang Xu; Hai-Meng Zhou It has been previously reported that, with a fluorescence probe formed from o-phthaldehyde (OPTA) and the thiol and amino groups at or near the active site of creatine kinase, inactivation and exposure of the probe take place simultaneously and well before...

...Eli I. Lev; Israel Hendler; Ran Siebner; Zeev Tashma; Michael Wiener; Ilan Tur-Kaspa Freezing of serum samples at -30 °C without protective agents is the simplest and least expensive method of storage in serum banks. We investigated the stability of creatine kinase (CK) in human sera after freezer...

...Joseph Devine Creatine kinase (CK) isoenzyme determinations have been performed on a series of specimens containing macro-CK, an atypical isoenzyme variant seen in approximately 1%of patients. These specimens were obtained from 2 different patients. Isoenzyme determinations were made using four...

... dehydrogenase aspartate aminotransferase alanine aminotransferase alkaline phosphatase creatine kinase arrhenius plots Original Papers Enzyme 32: l-l 1 (1984) 1606477 © 1984 S. Karger AG, Basel 0013-9432/84/0321-0001 $2.75/0 Evaluation of the Thermal Stability of Clinically Relevant Enzymes at 37 °C...

... The activities of 4 enzymes, i.e. alkaline phosphatase,γ-glutamyl transferase, lactate dehydrogenase and creatine kinase were studied in bronchial aspirates and serums from two groups of subjects, the first one was composed of 14 subjects without active bronchopulmonary pathology and the other...

... While studing the distribution of creatine kinase isoenzymes in the mucosa of the rat digestive tract, we found two predominant patterns, namely the esophagic pattern with predominant MM isoenzyme, and the gastrointestinal pattem with predominant BB isoenzyme. The quantitative distribution...

...Judi Weissinger; Paul Wolf; Colin Bloor Yucatan miniswine with systemic infections (C. pyogenes and S. marcescens) and accompanying elevated body temperature, also have increased serum creatine kinase (CK), lactate dehydrogenase (LD) and γ-globulin (GG) levels. The CK and LD levels increase...

... physically stressed by running 14 miles at 8 min/mile after 1 month of training. The effects of the different levels of conditioning on exertional rhabdomyolysis after the test run were determined by assaying serum samples for creatine kinase (CK) and myoglobin levels. Serum CK levels increased 98-294% above...

...G. Haralambie Creatine kinase (CK) was measured in muscle samples from 9 female and 9 male adult subjects using comparatively two procedures. The improved method, using N-acetylcysteine as activator gives results about 1.5 times higher than that with reduced glutathione. The significant correlation...

...Elena Tzvetanova Creatine kinase isoenzymes in sera and muscle biopsies obtained from 50 controls, 72 patients with progressive muscular dystrophy (PMD), 68 patients with other neuromuscular disorders, 17 carriers of Duchenne-type PMD and 15 patients with myocardial infarction were studied. MB...

...Paul L. Wolf; John C. Griddiths; Richard Erickson Increase in size of bone is characteristic of acromegaly. In addition, hypertrophy of other tissues including skeletal muscle and associated myopathy may occur. We recently found 10 U/l of isoenzyme creatine kinase 2 (MB) or 10.9% of total creatine...

.... In the experimental group 1, the animals were anaesthetized only. The plasma activities of the four enzymes measured — lactate dehydrogenase,aspartate aminotransferase, alanine aminotransferase, creatine kinase did not show any mentionable change during a time period of 6 h. In group 2 one hind limb of each animal...

...Paul Wolf; John Griffiths; John Koett; James Howell We recently found 17 U/l of isoenzyme creatine kinase (CK) 2 (MB), or 3.2% of total 533 U/l CK activity, in a patient with hypokalemic familial periodic paralysis who did not show clinical or EKG evidence of acute myocardial necrosis. The myopathy...

...J. Frei; M. Maillard; M. Markert; M. Aeilig Creatine kinase activity could be demonstrated in the cytosol of macrophages and polymorphonuclear leukocytes from guinea pig peritoneal exudates, in circulating mononuclear cells of blood donors and of a preleukemic patient, but not in human circulating...

...H.J. Kloosterboer; S.A. Stoker-de Vries; F.A. Hommes The activity of cytosolic creatine kinase in rat skeletal muscle rises stepwise during development. The increases occur simultaneously with transient increases in DNA content. The second increase is accompanied by a rise in total protein, soluble...