... potential precursors are reviewed; particular attention is given to their possible involvement under physiological conditions. The substrates considered are lactate, amino acids (particularly alanine, glutamine,serine, aspartate and hydroxyproline), glycerol and fatty acids. An attempt is made to assess...

...J. Patelski; Z. Waligóra; B. Zgorzalewicz; S. Szulc Activation of 22 protein amino acids in the presence of enzyme preparation from pig aortas was shown. Detailed parameters (pH, reaction time and velocity, substrate and enzyme concentrations) of the reaction measured by two methods, the formation...

...Dieter Häussinger; Wouter H. Lames; Antoon F.M. Moorman With respect to hepatocyte heterogeneity in ammonia and amino acid metabolism,two different patterns of sublobular gene expression are distinguished: ‘gradient-type’and ‘strict- or compartment-type’ zonation. An example for strict-type...

... and, therefore, the existence of early damage to the enzymes‘activating’ the free amino acids. These data represent an initial result to clarify the pathogenesis of the increase of free amino acids observed by the same authors in liver tissue during the acute phase of CCI(4) poisoning. 11 8 2017...