Mäusen wurde intraperitoneal 10'000 DL(60) von Virus-MHV-3 inokuliert. Während der verschiedenen Phasen der Infektion wurde der ATP-Gehalt des Lebergewebes bestimmt. Die Messungen wurden mit Luciferin-Luciferase nach Strehler und McElroy durchgeführt. 24 Stunden nach Inokulation wurde eine signifikante Abnahme des ATP-Gehalts der Leber festgestellt, die sich in den darauffolgenden Stunden noch verstärkte. Es wurden ferner histopathologische Befunde erhoben, die Virusvermehrungskinetik im Lebergewebe und die Veränderungen der Aktivitäten von Glutamat-Oxalacetat- Transaminase (GOT) und Glutamat-Pyruvat-Transaminase (GPT) im Serum untersucht.

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