L’induction chez le cobaye d’une péritonite stérile permet l’étude du retentissement d’un processus inflammatoire sur le métabolisme des leucocytes circulants et extravasés. On a envisagé le cas d’un exsudât ayant évolué durant 5 heures et dosé, dans divers homogénats, les activités biochimiques suivantes: glycolyse aérobie et anaérobie, protéolyse, phosphatases alcaline et acide. Le calcul algébrique répartit les activités globales mesurées entre les principaux types cellulaires des homogénats étudiés. Les résultats soulignent l’hétérogénéité biochimique de la population blanche. Granulocytes et lymphocytes, différents déjà chez le témoin, réagissent différemment à une même situation pathologique. En outre, un même type de cellule ne se comporte pas identiquement selon qu’il se trouve dans la circulation ou dans un exsudât. On discute de la signification physiologique de ces résultats.

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