Es werden enzymatische Methoden zur quantitativen Bestimmung von Acetacetat und D-(-)-3-Hydroxybutyrat im Blut beschrieben, die sich für Routine-Analysen eignen. Vorläufige Normal-Werte und das Verhältnis 3- Hydroxybutyrat : Acetacetat wurden für Gesunde und eingestellte Diabetiker ermittelt.

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