L’attività ATP-asica del siero, a pH acido ed alcalino, è significativamente aumentata nei pazienti portatori di ipertensione essenziale e di ipertensione renale. Tale attività enzimatica non subisce alcun incremento in pazienti affetti da nefropatie in fase non ipertensiva. Essa è significativamente aumentata anche in soggetti non ipertesi affetti da spasmo della muscolatura liscia bronchiale. Viene discussa la possibilità di un perturbamento metabolico dei gruppi fosforici ad alto livello energetico nei pazienti affetti da ipertensione arteriosa e viene prospettata l’ipotesi che l’incremento della ATP-asi serica possa trarre origine dallo stato di contrazione della muscolatura liscia arteriolare.

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