... treatment (ODT) for a prolonged-release buprenorphine (PRB) injection according to their prior ODT (buprenorphine/naloxone [B/N] or methadone). Methods: This was an observational, retrospective/cross-sectional, multicentre study of adult patients diagnosed with OUD on ODT. Data collected from diaries were...

... replacement therapy is an effective treatment for opioid-dependent patients, there is little knowledge about physical and psychological functioning of QoL for different treatment options. Objectives: Altogether, 248 opioid-dependent patients receiving substitution treatment with either methadone/levomethadone...

... methadone (MTD) is the most commonly used, fewer data are available on alternative opioid agonist. The aim of this study was to assess the efficacy of buprenorphine (BUP) and slow-released morphine compared to MTD with regard to the reduction of concomitant heroin and cocaine use. Methods: This cross...

... of intravenous injection of methadone (MET), buprenorphine (BUP), BUP-naloxone (NLX), OMT dosage and type, experience of and reason for misuse, concurrent intravenous benzodiazepine misuse, pattern of -misuse in relation to admission to the addiction unit and ER -admissions because of misuse. According...

...Lucio Boglione; Amedeo De Nicolò; Simone Mornese Pinna; Jessica Cusato; Giuseppe Cariti; Giovanni Di Perri; Antonio D’Avolio Backround: The effect of methadone (MET) during therapy with novel direct-acting antiviral agents is still not fully understood. Currently, no data are available about...

..., instructions or products referred to in the content or advertisements. Heroin Opioids Methadone Buprenorphine Treatment monitoring Public health Drug policy Opioid dependence is often a chronic relapsing disorder that is associated with increased morbidity, mortality and crime. Worldwide...

...Michael Soyka; Jens Strehle; Jürgen Rehm; Gerhard Bühringer; Hans-Ulrich Wittchen Background: In many countries, the opioid agonists, buprenorphine and methadone, are licensed for maintenance treatment of opioid dependence. Many short-term studies have been performed, but little is known about long...

... and long-term exposure to opioid receptor stimulation (heroin dependence, methadone maintenance treatment, methadone dosage), the potentially related hormonal changes reflecting hypothalamus-pituitary-gonadal axis function and prolactin (PRL) pituitary release, the role of adverse childhood experiences...

..., instructions or products referred to in the content or advertisements. Misuse Diversion Buprenorphine Methadone Opioid substitution treatment Opioid dependence is a problem that exacts a significant toll on public health and generates criminal, health and economic costs quantifiable...

...Gabrielle K. Welle-Strand; Svetlana Skurtveit; Lars Tanum; Helge Waal; Brittelise Bakstad; Lisa Bjarkø; Edle Ravndal Background: The tapering of methadone or buprenorphine during pregnancy is an understudied and controversial issue. The aim of this study was to determine to what extent women...

...Michael Soyka Maintenance therapy with methadone or buprenorphine is an established and first-line treatment for opioid dependence. Clinical studies indicate that about a third of patients in opioid maintenance therapy show increased alcohol consumption and alcohol use disorders. Comorbid alcohol...

...Uwe Verthein; Thilo Beck; Christian Haasen; Jens Reimer Background: Opioid maintenance treatment is the option of choice to stabilize opioid-dependent patients. Whilst efficacy of methadone and buprenorphine has been studied extensively, fewer data on slow-release oral morphine are available. Aims...

... to methadone, 9 children (mean age = 52.41 months, SD = 1.42) prenatally exposed to buprenorphine and 25 nonexposed comparison children (mean age = 51.44 months, SD = 1.31) were tested. Visual selective attention was measured with a Tobii 1750 Eye Tracker using a spatial negative priming paradigm. Attention...

...Colin R.W. Baird; Pauline Fox; Lesley A. Colvin Background/Aims: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone. Methods: A questionnaire-based...

... dead was given by the Norwegian Directorate of Health. 23 04 2012 9 10 2012 21 12 2012 Somatic morbidity Opioid maintenance treatment Opioid dependence Buprenorphine Cohort study Comorbidity Methadone Treatment interruption Heroin and overdose Opioid...

...Peng-Wei Wang; Hung-Chi Wu; Huang-Chi Lin; Chia-Nan Yen; Yi-Chun Yeh; Kuan-Sheng Chung; Hsun-Cheng Chang; Cheng-Fang Yen Aim: Little is known about whether heroin-dependent individuals receiving methadone maintenance treatment (MMT) who were discharged involuntarily and against medical advice (DAMA...

... double-blind controlled randomized clinical trials using twice-a-day immediate-release oral diacetylmorphine (DAM) in heroin-dependent patients, by means of measuring the capacity of oral DAM to block opiate withdrawal and clinicians’ ability to distinguish it from morphine and methadone...

.... Methods: Site differences of a multi-center prospective double-blind, double-dummy randomized controlled trial (7 centers: Central Europe (Vienna)/USA (3 urban/3 rural centers)) comparing safety and efficacy of methadone and buprenorphine in pregnant opioid-dependent women and their neonates. Results...

.... Methadone Buprenorphine Opiate-related disorders Evidence-based guidelines European Addiction Research Research Report Eur Addict Res 2011;17:44 54 DOI: 10.1159/000320576 Published online: October 26, 2010 Barriers to Opioid Substitution Treatment Access, Entry and Retention: A Survey of Opioid Users...

... diagnoses on problem severity, psychiatric comorbidity, and quality of life in methadone-maintained patients. Methods: 193 patients in long-term methadone maintenance treatment (MMT) were assessed for ADHD through a semi-structured interview. Psychiatric disorders and SUD were assessed with the MINI...