... described in early abstinent alcohol-dependent patients. In a longitudinal approach, we investigated whether changes in AVP and ANP serum levels correlated to cytosine-phosphatidyl-guanine (CpG) methylation of the respective gene promoters on days 1, 7 and 14 of alcohol withdrawal. We analyzed the blood...

...Deniz Karagülle; Annemarie Heberlein; Julia Wilhelm; Helge Frieling; Johannes Kornhuber; Stefan Bleich; Thomas Hillemacher Aims: Alcohol withdrawal seizures (AWS) are among the most important possible complications during the detoxification treatment of alcohol-dependent patients. Pharmacological...

... drinking. One week after alcohol withdrawal, selective cognitive dysfunction was observed in 60% of patients, concerning visuospatial functions and the psychomotor functions subtending end-oriented behavior which depends on the prefrontal cortex (executive functions). After 6 months of abstinence...

..., possibly genetic, factor; (3) depression may be a result of alcoholism: either induced by heavy alcohol consumption, as a consequence of alcohol withdrawal or as a psychoreactive phenomenon. Clinical guidelines for pharmaco- and psychotherapy of depression in patients suffering from alcoholism are outlined...

...Young-Sik Lee; Sam-Wook Choi; Doug-Hyun Han; Dai-Jin Kim; Keun-Ho Joe Aim: The purpose of this study was to investigate the role of serotonergic genes in the development of alcohol dependence. The manifestation of alcohol withdrawal symptoms related to serotonergic polymorphisms in alcoholics...