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1-4 of 4
Keywords: Tetrahydroaminoacridine
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Journal Articles
Journal:
Dementia
Dementia (1994) 5 (6): 295–301.
Published Online: 02 November 1994
.... The most consistent neurochemical changes in DAT are reductions in the cholinergic system. The major pharmacological approach today in DAT is based on the cholinergic theory assuming that acetylcholine has a major cortical impact on cognitive processes. Tetrahydroaminoacridine (THA, tacrine) is a centrally...
Journal Articles
Journal:
Dementia
Dementia (1993) 4 (1): 54–58.
Published Online: 05 February 1993
...Kari Alhainen; Eeva-Liisa Helkala; Paavo Riekkinen Fourteen patients with probable Alzheimer''s disease (AD) participated in an open tetrahydroaminoacridine (THA) treatment trial. Before initiation of THA treatment, a brief battery of neuropsychological tests was performed by an experienced...
Journal Articles
L. Minthon, L. Gustafson, G. Dalfelt, B. Hagberg, K. Nilsson, J. Risberg, I. Rosén, B. Seiving, P.E. Wendt
Journal:
Dementia
Dementia (1993) 4 (1): 32–42.
Published Online: 05 February 1993
... is treatment with a cholinesterase inhibitor such as tetrahydroaminoacridine (THA). THA treatment of 17 patients with DAT was studied with a double-blind crossover design with three types of treatment, THA + lecithin, THA + placebo and placebo + placebo. Each treatment period was 6 weeks with wash out periods...
Journal Articles
Journal:
Dementia
Dementia (1991) 2 (4): 200–206.
Published Online: 12 December 1991
...Gilles Chatellier; Lucette Lacomblez; Christian Derouesne Tetrahydroaminoacridine (THA) is a potent centrally acting anticholinesterase which has been used by anesthesiologists since the 1940s. The report by Summers et al. of encouraging results with this compound in Alzheimer''s disease...
