...Fortuné M.K. Elekonawo; Manon M.D. van der Meeren; Geert A. Simkens; Johannes H.W. de Wilt; Ignace H. de Hingh; Andreas J.A. Bremers Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is associated with considerable postoperative morbidity, including ileus...

... continue to evolve. In this review, we highlight current trends in neoadjuvant chemotherapy, surgical resection, and other multimodality approaches for patients with LA-PDAC. Despite promising early results, additional work is needed to more accurately and appropriately tailor treatment for patients...

..., effective adjuvant chemotherapy for lymph node positive primary colon cancer was introduced. This study evaluated the prognostic value of primary lymph node status in patients with resectable metachronous CRLM in the era of effective systemic therapy. Methods: Between January 2000 and December 2011, all...

... lymphadenectomy) and their outcomes result in significant geographical variation in preferred adjuvant treatments. Currently, oral fluoropyrimidine-based postoperative adjuvant chemotherapy, 1 year of S-1 chemotherapy, or capecitabine plus oxaliplatin for 6 months are the standards of care after curative...

.... This review focuses on comparative trials studying the use of adjuvant therapy with chemotherapy plus immunotherapy in the treatment of patients with curatively resected gastric cancer. Preoperative and intraperitoneal therapy, and therapy for advanced or recurrent gastric cancer are also discussed...

...Sébastien Gaujoux; Diane Goéré; Frédéric Dumont; Amine Souadka; Clarisse Dromain; Michel Ducreux; Dominique Elias Missing metastases, also called vanishing or disappearing liver metastases, concern about 5% of patients with colorectal liver metastasis undergoing chemotherapy, and this phenomenon...

... and shapes future trials in treatment of operable rectal cancer. Methods: PubMed and MEDLINE search. Results: RT reduces local recurrence and pre-operative treatment is superior to post-operative treatment. Longer interval to surgery and concurrent chemotherapy are associated with greater downstaging...

... with chemotherapy first, doing the liver surgery second, and performing the colorectal surgery last – is theoretically appealing as it avoids the risk of metastatic progression during treatment of the primary tumor. The present series updates on a previously reported pilot experience. Patients and Methods: 35...

...Eddie K. Abdalla; Jean-Nicolas Vauthey Background: Improved efficacy of chemotherapy for treatment of colorectal liver metastases (CLM) has renewed interest in the use of systemic treatment as part of a ‘potentially curative’ treatment plan for patients with CLM. Controversy exists regarding...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hepatocellular cancer Radiation therapy Chemotherapy Chemoembolization Regional chemotherapy Dig Surg 1995;12:73-78 James V. Sitzmann Ross A. Abrams Johns Hopkins Medical...

...Jürgen Finke; Rupert Engelhardt Patients with advanced gastric cancer benefit from chemotherapy as compared to best supportive care only. Several agents show activity against metastatic gastric cancer, like 5-fluorouracil (5-FU), etoposide, mitomycin C, doxorubicin, epirubicin, cisplatin. However...

... located in the lower portion of the esophagus. The lower third of the esophagus and cardia were resected, together with regional lymph nodes. Subsequently 10 courses of chemotherapy were administered and immunotherapy was also added after multiple metastases were found in the liver and lung. He died...

... external beam radiotherapy and adjuvant chemotherapy alone are reviewed. More recently, combined multimodality adjuvant therapy has been used following ‘curative resection’ for pancreatic cancer, and the current status concerning the use of such treatment is addressed. There is insufficient evidence...

.... Addition of a radiation sensitizer (misonidazole) and chemotherapy (FAM) seems to improve the results. Pancreas Cancer Inoperable metastases Treatment Intraoperative radiation Electron beam Linear accelerator Chemotherapy Radiation sensitizers © 1984 S. Karger AG, Basel 1984 Copyright...

...Sandeep Goyle; Anthony Maraveyas Colorectal cancer is the most commonly diagnosed cancer in the EU. Various randomised studies have shown a survival benefit with chemotherapy in the adjuvant setting. Adjuvant chemotherapy with 5-fluorouracil/folinic acid (5FU/FA) for 6 months after curatively...

.... There was a survival benefit for chemotherapy irrespective of the type of surgery or post-operative complications. Conclusions: The KW and PP-KW procedures did not significantly influence the hazard of death in the presence of tumour staging, demonstrating that ESPAC-1 surgeons showed good judgement in their choice...

...G. Fusai; B.R. Davidson Liver resection can provide long-term survival and cure for patients with colorectal liver metastases but is feasible in only 15–25% of patients. In the last few years several major developments have contributed to increase this resectability rate. Neo-adjuvant chemotherapy...

... to in the content or advertisements. Esophageal carcinoma Esophageal resection Postoperative morbidity Postoperative mortality Risk factors Working capacity Endosonography Radiotherapy Chemotherapy Gastroesophageal junction, carcinoma Thoracoabdominal resections for cancer of esophagus...

...Kazuhide Kumagai; Kouji Shimizu; Kouki Masuo; Kennichi Yamagata; Takayuki Tanaka This study was designed to evaluate the efficacy of preoperative chemotherapy and to investigate the relationship between the histopathologic response and prognosis in patients with colorectal carcinoma. Thirty-six...