... were noted in 12, a mass in 4, a painful bulging or rectal examination in 6. The diagnosis was confirmed by laparotomy in 2 cases by a supposed association with (a) long-term anticoagulant therapy for a major cardiovascular disease (11 cases); (b) a fall in the prothrombin time below 10% (11 cases...

...M. Negri; S. Slutzki; Z. Halpern; A. Zisman; A. Halevy Intra- and retroperitoneal bleeding may be associated with anticoagulant therapy and presents the gastroenterological surgeon with a diagnostic and therapeutic dilemma. Although these rare types of bleeding may be spontaneous, minimal trauma...