A comparison was made between the effect of the Gambee technique with inversion of the serosa and a submucosa technique on wound healing in small bowel anastomoses of 15 pigs. The submucosa technique avoids a broad serosal contact by burying the horizontally placed suture sling in the submucosal layer. Polydioxanon 4-0 and 6-0 served as suture material. Two anastomoses of each technique were constructed in one animal. Five animals were sacrificed after 4 days, 3 weeks, and 3 months, respectively. The anastomoses were evaluated by gross appearance, microangiography and histology. The submucosa technique resulted in a significant smaller scar with fewer necrotic areas (p < 0.01). It did not compromise the blood vessels in the knot area. This improved wound healing demonstrates that anastomotic healing does not necessitate broad serosal contact. Therefore, the submucosa technique may be considered for anastomoses of the compromised gut.

Keywords:
Suture technique, Single-layer anastomosis, Serosa, Microangiography
This content is only available via PDF.
© 1992 S. Karger AG, Basel
1992
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.