1,780 patients have undergone gastrectomy for gastric cancer in our clinic, and the chronological trends in the pathological findings of this cancer have been evaluated. Recently, the proportion of patients with early cancer was markedly increased: from 22.4% in the 1960s to 29.6% in the 1970s and 39.2% in the 1980s. In terms of age distribution, a decrease in the proportion of patients under 50 years of age (27.6,26.4 and 18.4% in the 1960s, 1970s, and 1980s, respectively) and an increase in the proportion of patients over 70 years of age (9.4,16.5 and 22.8% in the 1960s, 1970s and 1980s, respectively) were noticed. The decrease may be related to westernization of dietary habits in Japan after World War II. In terms of pathological findings, macroscopically there was a decrease in the elevated type of early cancer (23.9% in the 1960s, 18.9% in the 1970s and 10.5% in the 1980s) and in the localized type of advanced cancer (36.6, 23.5 and 27.9% in the 1960s, 1970s and 1980s, respectively). Microscopically, there was a decrease in the proportion of the intestinal type, such as papillary adenocarcinoma (from 37.7% in the 1960s to 22.2% in the 1980s in early cancers; and from 18.5% in the 1960s to 13.2% in the 1980s in advanced cancer). Thus, a westernization of the characteristics of gastric cancer was observed, and consequently, in Japan, a reduction in the incidence of gastric cancer is expected. As the rates of resectability and curative resectability have improved, the 5-year survival rate has improved chronologically, with rates of 60.7, 67.6 and 76.7% in the 1960s, 1970s and 1980s, respectively.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.