Abstract
Duodenogastric reflux (DGR) was quantified in 40 patients, 10 of them being healthy subjects used as a control group. The remaining 30 underwent gastric surgery and fell into two groups according to their medical history: symptomatic and asymptomatic patients. As a DGR study method, 24-hour gastric pH measurement was used, in association with the determination of bile acids in aspirated gastric juice. Bile acid determination was used in order to differentiate the pH increases due to hyposecretion from those due to DGR. Our results show that, in symptomatic patients, the mean size of the reflux areas (pH > 4) and the mean total bile acid concentration are statistically significantly larger than those of asymptomatic patients (p < < 0.01).
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© 1988 S. Karger AG, Basel
1988
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